Personal profile
In Korean
홍장원 교수(의과대학 의학과)
Education
o (2005) M.D., College of Medicine, Hallym University
o (2007) M.S., Department of Pharmacology, College of Medicine, Hallym University
o (2011) Ph.D., Department of Pharmacology, College of Medicine, Hallym University
o (2007) M.S., Department of Pharmacology, College of Medicine, Hallym University
o (2011) Ph.D., Department of Pharmacology, College of Medicine, Hallym University
Professional Experience
o (2021~Present) Associate Professor, Kyungpook National University, Daegu
o (2016~2021) Assistant Professor, Kyungpook National University, Daegu
o (2012~2016) Research Professor, Hallym University, Chuncheon
o (2010~2012) Member of Biosafery Council, Ministry of National Defense, Republic of Korea Army
o (2009~2012) Medical Officer, Captain, Department of Chemical and Biological Warfare, The Armed Forces Medical Research Institute, Dajeon, Republic of Korea Army
o (2016~2021) Assistant Professor, Kyungpook National University, Daegu
o (2012~2016) Research Professor, Hallym University, Chuncheon
o (2010~2012) Member of Biosafery Council, Ministry of National Defense, Republic of Korea Army
o (2009~2012) Medical Officer, Captain, Department of Chemical and Biological Warfare, The Armed Forces Medical Research Institute, Dajeon, Republic of Korea Army
Research Interests
Characterization of the physioloigcal function of neutrophils
Identification on the role of innate immune cells in the pathogenesis of disease
Research on metabolism in innate immune cells
Bioinformatic analysis on innate immune cells (scRNAseq, bulk RNAseq)
Identification on the role of innate immune cells in the pathogenesis of disease
Research on metabolism in innate immune cells
Bioinformatic analysis on innate immune cells (scRNAseq, bulk RNAseq)
Major Research Achievements
o Diabetes Primes Neutrophils for Neutrophil Extracellular Trap Formation through Trained Immunity, Research, 2024, 23:7:0365 (IF=11.0)
o Neutrophil-derived trail is a proinflammatory subtype of neutrophil-derived extracellular vesicles, Theranostics, 2021; 11(6):2770-2787 (IF=12.2)
o Autophagy primes neutrophils for neutrophil extracellular trap formation during sepsis, Am J Respir Crit Care Med. 2017 Sep 1;196(5):577-589 (IF=24.7)
o Neutrophil-derived trail is a proinflammatory subtype of neutrophil-derived extracellular vesicles, Theranostics, 2021; 11(6):2770-2787 (IF=12.2)
o Autophagy primes neutrophils for neutrophil extracellular trap formation during sepsis, Am J Respir Crit Care Med. 2017 Sep 1;196(5):577-589 (IF=24.7)
url
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Usefulness of Delta Neutrophil Index (DNI) for Prediction of 28 Day Mortality in Patients with Pneumonia-Induced Sepsis in the Intensive Care Unit
Moon, S. Y., Park, Y. B., Hong, C. W., Park, S., Sim, Y. S., Ko, Y. & Park, S. Y., Mar 2025, In: Journal of Clinical Medicine. 14, 6, 2002.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Ferroptosis in neutrophils
Lee, Y. B., Shin, H. W., Shrestha, S., Kim, J. K., Jung, S. J., Shin, M. S. & Hong, C. W., 1 May 2025, In: Journal of Leukocyte Biology. 117, 5, qiaf039.Research output: Contribution to journal › Review article › peer-review
15 Scopus citations -
Neutrophils in MASLD and MASH
Shrestha, S., Jeon, J. H. & Hong, C. W., 2025, In: BMB Reports. 58, 3, p. 116-123 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
Single-cell RNA sequencing revealed the role of the Th17 pathway in the development of anti-human leukocyte antigen antibodies in a highly sensitized mouse model
Lee, H., Shin, Y. J., Fang, X., Cui, S., Lim, S. W., Lee, S. Y., Eum, S. H., Min, J. W., Hong, C. W., Lee, H. O., Cho, M. L., Oh, E. J., Yang, C. W. & Chung, B. H., Nov 2025, In: Kidney Research and Clinical Practice. 44, 6, p. 960-973 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Comprehensive overview of the role of mitochondrial dysfunction in the pathogenesis of acute kidney ischemia-reperfusion injury: a narrative review
Kim, M. J., Oh, C. J., Hong, C. W. & Jeon, J. H., Apr 2024, In: Journal of Yeungnam Medical Science. 41, 2, p. 61-73 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access10 Scopus citations