Calculated based on number of publications stored in Pure and citations from Scopus
20022024

Research activity per year

Personal profile

In Korean

이동석 교수(자연과학대학 생명공학부)

Education

o (1994) B.A., Kyungpook National University, Daegu, Korea
o (1997) M.A., The University of Tokyo, Tokyo , Japan
o (2000) Ph.D., The University of Tokyo, Tokyo , Japan

Professional Experience

o (2007~Present) Professor, Kyungpook National University, Daegu, Korea
o (2020~Present) Director, BK21 FOUR KNU Creative BioResearch Group, Daegu, Korea
o (2014~2020) Director, BK21 Plus KNU Creative BioResearch Group, Daegu, Korea
o (2006~2007) Assistant Professor, Kangwon National University, Chuncheon, Korea
o (2002~2006) Senior Researcher, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea
o (2000~2001) Visiting researcher, National Institutes of Health, NC, USA

Research Interests

Neuroscience, Neurodegenrative diseases, Alzheimer's Disease, Multiple scleroisis, Neural cells, Glial cells, Mitochondria, Mitochondrial dynamics, Organelle, Inflammation, Obesity, Antioxidants, Peroxiredoxins, Reactive Oxygen Species, Animal models

Major Research Achievements

o Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways
o Mitochondrial dynamics modulate the expression of pro‐inflammatory mediators in microglial cells
o Enhancement of target specificity of CRISPR–Cas12a by using a chimeric DNA–RNA guide
o Peroxiredoxin 5 ameliorates obesity-induced non-alcoholic fatty liver disease through the regulation of oxidative stress and AMP-activated protein kinase signaling
o Peroxiredoxin 5 deficiency exacerbates iron overload-induced neuronal death via ER-mediated mitochondrial fission in mouse hippocampus

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Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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