Personal profile
In Korean
강효정 교수(약학대학 약학과)
Education
o (1998) B.A., Korea University, Seoul, Korea
o (2000) M.A.,Korea University, Seoul, Korea
o (2024) Ph.D., Texas A&M University, College Station, TX, USA
o (2000) M.A.,Korea University, Seoul, Korea
o (2024) Ph.D., Texas A&M University, College Station, TX, USA
Professional Experience
o (2022.04~Present) Professor, Kyungpook National University, Daegu, Korea
o (2017.04~2022.03) Associated Professor, Kyungpook National University, Daegu, Korea
o (2011.03~2017.03) Assistant Professor, Kyungpook National University, Daegu, Korea
o (2007.08~2011.02) Postdoctoral Researcher, The Wistar Institute, Philadelphia, PA, USA
o (2005.01~2007.08) Postdoctoral Researcher, Texas A&M Health Science Center, College Station, TX, USA
o (200.01~2004.12) Research Assistant, Texas A&M University, College Station, TX, USA
o (2017.04~2022.03) Associated Professor, Kyungpook National University, Daegu, Korea
o (2011.03~2017.03) Assistant Professor, Kyungpook National University, Daegu, Korea
o (2007.08~2011.02) Postdoctoral Researcher, The Wistar Institute, Philadelphia, PA, USA
o (2005.01~2007.08) Postdoctoral Researcher, Texas A&M Health Science Center, College Station, TX, USA
o (200.01~2004.12) Research Assistant, Texas A&M University, College Station, TX, USA
Research Interests
0 Epstein-Barr virus pathogenesis and oncogenic mechanisms
0 Oncolytic virotherapy development
0 Coronavirus replication and gene expression
0 Epigenetic mechanisms in cancer and drug development
0 Oncolytic virotherapy development
0 Coronavirus replication and gene expression
0 Epigenetic mechanisms in cancer and drug development
Major Research Achievements
1) Epstein-Barr Virus (EBV) Pathogenesis and Oncogenic Mechanisms:
o Elucidating the molecular mechanisms underlying EBV-induced pathogenesis and oncogenesis.
o Investigating the role of epigenetic modifications, particularly DNA methylation, in EBV-associated cancers.
o Identifying and characterizing novel CTCF binding sites in the EBV genome and their impact on viral gene expression and host cell
transformation.
2) Oncolytic Virotherapy Development:
o Developing and evaluating oncolytic viruses based on adenovirus and HSV-1 platforms for cancer treatment.
o Targeting viral lytic genes and optimizing therapeutic efficacy and safety of oncolytic viruses.
3) Coronavirus Replication and Gene Expression:
o Investigating the molecular mechanisms of coronavirus replication, including the role of 5'UTR stem-loop structures.
o Understanding the regulation of subgenomic RNA production in coronaviruses.
4) Epigenetic Mechanisms in Cancer and Drug Development:
o Elucidating the role of epigenetic modifications, such as DNA methylation, in cancer development and progression.
o Developing novel therapeutic strategies Targeting epigenetic regulators for cancer treatment.
o Elucidating the molecular mechanisms underlying EBV-induced pathogenesis and oncogenesis.
o Investigating the role of epigenetic modifications, particularly DNA methylation, in EBV-associated cancers.
o Identifying and characterizing novel CTCF binding sites in the EBV genome and their impact on viral gene expression and host cell
transformation.
2) Oncolytic Virotherapy Development:
o Developing and evaluating oncolytic viruses based on adenovirus and HSV-1 platforms for cancer treatment.
o Targeting viral lytic genes and optimizing therapeutic efficacy and safety of oncolytic viruses.
3) Coronavirus Replication and Gene Expression:
o Investigating the molecular mechanisms of coronavirus replication, including the role of 5'UTR stem-loop structures.
o Understanding the regulation of subgenomic RNA production in coronaviruses.
4) Epigenetic Mechanisms in Cancer and Drug Development:
o Elucidating the role of epigenetic modifications, such as DNA methylation, in cancer development and progression.
o Developing novel therapeutic strategies Targeting epigenetic regulators for cancer treatment.
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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Anticancer Activity of Paclitaxel-Loaded Mesoporous Silica Nanoparticles in B16F10 Melanoma-Bearing Mice
Lee, J., Kim, J. M., Baek, Y. J., Kang, H., Choi, M. K. & Song, I. S., Aug 2025, In: Pharmaceutics. 17, 8, 1042.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Development of adenovirus-based oncolytic virus to induce EBV lytic reactivation
Lee, S. H., Byun, H., Seo, D., Cho, M., Kim, J. H., Kang, B. W., Cho, H. & Kang, H., Nov 2025, In: Gastric Cancer. 28, 6, p. 1125-1143 19 p.Research output: Contribution to journal › Article › peer-review
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Dihydrotestosterone-androgen receptor signaling suppresses EBV-positive gastric cancer through DNA demethylation-mediated viral reactivation
Cho, M., Byun, H., Lee, S. H., Youn, S., Jung, I., Jung, J., Lee, J., Cho, H. & Kang, H., Sep 2025, In: Gastric Cancer. 28, 5, p. 776-798 23 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Inhibition of MCP1 (CCL2) Enhances Antitumor Activity of NK Cells Against HCC Cells Under Hypoxia
Lee, H. H., Kim, J., Park, E., Kang, H. & Cho, H., May 2025, In: International Journal of Molecular Sciences. 26, 10, 4900.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Blocking CXCR3B Expression Increases Tumor Aggressiveness in Hepatocellular Carcinoma
Lee, H. H., Oh, S., Kang, H. & Cho, H., Dec 2024, In: Anticancer Research. 44, 12, p. 5293-5301 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations