Research output per year
Research output per year
Personal profile
In Korean
김인겸 교수(의과대학 의학과)
Education
o (1992) Ph.D., Pharmacology, Kyungpook National University, Korea
o (1989) MSc., Pharmacology, Kyungpook National University, Korea
o (1986) M.D., Kyungpook National University, Korea
o (1989) MSc., Pharmacology, Kyungpook National University, Korea
o (1986) M.D., Kyungpook National University, Korea
Professional Experience
o (2023~Present) Korean Association of Basic Medical Scientists, President
o (2021~Present) Asia-Pacific Federation of Pharmacologists, Councilor
o (2010~Present) Director, Cardiovascular Research Institute, Kyungpook National University, Korea
o (2006~Present) Professor, Kyungpook National University, Korea
o (2021~Present) Asia-Pacific Federation of Pharmacologists, Councilor
o (2010~Present) Director, Cardiovascular Research Institute, Kyungpook National University, Korea
o (2006~Present) Professor, Kyungpook National University, Korea
Research Interests
o Mechanisms of development of essential hypertension and cardiometabolic syndrom
o Immune regulation
o Transcriptomics
o Vascular stresses
o Salt-sensitivity
o Metabolites of gut microbiota
o Epigenetic modifications
o Immune regulation
o Transcriptomics
o Vascular stresses
o Salt-sensitivity
o Metabolites of gut microbiota
o Epigenetic modifications
Major Research Achievements
o Single cell transcriptome analyses reveal the roles of B cells in fructose-induced hypertension.
o Dahl salt-resistant rats are protected against angiotensin II-induced hypertension.
o Maternal high-fructose intake induces multigenerational activation of the renin-angiotensin-aldosterone system.
o Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes
o Histone Deacetylase Inhibition Attenuates Transcriptional Activity of Mineralocorticoid Receptor through its Acetylation and Prevents Development of Hypertension.
o Dahl salt-resistant rats are protected against angiotensin II-induced hypertension.
o Maternal high-fructose intake induces multigenerational activation of the renin-angiotensin-aldosterone system.
o Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes
o Histone Deacetylase Inhibition Attenuates Transcriptional Activity of Mineralocorticoid Receptor through its Acetylation and Prevents Development of Hypertension.
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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Akkermansia muciniphila extracellular vesicles have a protective effect against hypertension
Kim, J. Y., Kim, C. W., Oh, S. Y., Jang, S., Yetunde, O. Z., Kim, B. A., Hong, S. H. & Kim, I., Jun 2024, In: Hypertension Research. 47, 6, p. 1642-1653 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Hypertonic Salt Solution Enhances Inflammatory Responses in Cultured Splenic T-Cells from Dahl Salt-Sensitive Rats but Not Dahl Salt-Resistant Rats
Jang, S., Kim, J. Y., Kim, C. W. & Kim, I., Oct 2023, In: Journal of Cardiovascular Development and Disease. 10, 10, 414.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Single cell transcriptome analyses reveal the roles of B cells in fructose-induced hypertension
Kim, C. W., Joo, S. Y., Kim, B., Kim, J. Y., Jang, S., Tzeng, S. J., Lee, S. J., Kim, M. & Kim, I., 2023, In: Frontiers in Immunology. 14, 1279439.Research output: Contribution to journal › Article › peer-review
Open Access -
T helper cell polarity determines salt sensitivity and hypertension development
Kim, J. Y., Lee, S., Jang, S., Kim, C. W., Gu, B. H., Kim, M. & Kim, I., Sep 2023, In: Hypertension Research. 46, 9, p. 2168-2178 11 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Dahl Salt-Resistant Rat Is Protected against Hypertension during Diet-Induced Obesity
Lee, S., Jang, S., Kim, J. Y. & Kim, I., Sep 2022, In: Nutrients. 14, 18, 3843.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations