Personal profile
In Korean
김인겸 교수(의과대학 의학과)
Education
o (1992) Ph.D., Pharmacology, Kyungpook National University, Korea
o (1989) MSc., Pharmacology, Kyungpook National University, Korea
o (1986) M.D., Kyungpook National University, Korea
o (1989) MSc., Pharmacology, Kyungpook National University, Korea
o (1986) M.D., Kyungpook National University, Korea
Professional Experience
o (2023~Present) Korean Association of Basic Medical Scientists, President
o (2021~Present) Asia-Pacific Federation of Pharmacologists, Councilor
o (2010~Present) Director, Cardiovascular Research Institute, Kyungpook National University, Korea
o (2006~Present) Professor, Kyungpook National University, Korea
o (2021~Present) Asia-Pacific Federation of Pharmacologists, Councilor
o (2010~Present) Director, Cardiovascular Research Institute, Kyungpook National University, Korea
o (2006~Present) Professor, Kyungpook National University, Korea
Research Interests
o Mechanisms of development of essential hypertension and cardiometabolic syndrom
o Immune regulation
o Transcriptomics
o Vascular stresses
o Salt-sensitivity
o Metabolites of gut microbiota
o Epigenetic modifications
o Immune regulation
o Transcriptomics
o Vascular stresses
o Salt-sensitivity
o Metabolites of gut microbiota
o Epigenetic modifications
Major Research Achievements
o Single cell transcriptome analyses reveal the roles of B cells in fructose-induced hypertension.
o Dahl salt-resistant rats are protected against angiotensin II-induced hypertension.
o Maternal high-fructose intake induces multigenerational activation of the renin-angiotensin-aldosterone system.
o Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes
o Histone Deacetylase Inhibition Attenuates Transcriptional Activity of Mineralocorticoid Receptor through its Acetylation and Prevents Development of Hypertension.
o Dahl salt-resistant rats are protected against angiotensin II-induced hypertension.
o Maternal high-fructose intake induces multigenerational activation of the renin-angiotensin-aldosterone system.
o Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes
o Histone Deacetylase Inhibition Attenuates Transcriptional Activity of Mineralocorticoid Receptor through its Acetylation and Prevents Development of Hypertension.
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Collaborations and top research areas from the last five years
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Increased lamina propria B cells play roles in fructose-induced hypertension of Dahl salt-sensitive rats
Jang, S., Kim, C. W., Olarinoye, Z. Y., Akter, S. & Kim, I., 15 Jan 2025, In: Life Sciences. 361, 123314.Research output: Contribution to journal › Article › peer-review
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Single-cell RNA sequencing reveals that a high salt diet increases IL6R-JAK1-STAT3 gene signaling pathway activity in intestinal B cells and Tfh cells of salt-sensitive hypertension animal model
Joo, S. Y., Lee, S. J., Lee, S. J., Seo, S. A., Kim, C. W., Hong, S. H., Kim, I. K. & Kim, M., Dec 2025, In: Scientific Reports. 15, 1, 25756.Research output: Contribution to journal › Article › peer-review
Open Access -
Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice
You, Y. S., Chang, W. T., Hsu, C. L., Wang, H. Y., Lu, Y. F., Kim, I. K. & Tzeng, S. J., 2025, In: Frontiers in Immunology. 16, 1548814.Research output: Contribution to journal › Article › peer-review
Open Access -
Akkermansia muciniphila extracellular vesicles have a protective effect against hypertension
Kim, J. Y., Kim, C. W., Oh, S. Y., Jang, S., Yetunde, O. Z., Kim, B. A., Hong, S. H. & Kim, I., Jun 2024, In: Hypertension Research. 47, 6, p. 1642-1653 12 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Differential gene expression in the kidneys of SHR and WKY rats after intravenous administration of Akkermansia muciniphila-derived extracellular vesicles
Olarinoye, Z. Y., Kim, C. W., Kim, J. Y., Jang, S. & Kim, I., Dec 2024, In: Scientific Reports. 14, 1, 20056.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations