Research output per year
Research output per year
Personal profile
In Korean
최제용 교수(의과대학 의학과)
Education
o (1988) B.S., Kyungpook National University(KNU), Dentistry, Daegu, South Korea
o (1990) M.A., Kyungpook National University, Biochemistry
o (1994) Ph.D., Kyungpook National University, Biochemistry
o (1990) M.A., Kyungpook National University, Biochemistry
o (1994) Ph.D., Kyungpook National University, Biochemistry
Professional Experience
o (2021~present) Professor, Department of Biochemistry & Cell Biology, School of Medicine, KNU, Daegu, Korea
o (2018~2021) Advisory board member, Science and Technology Policy Institute (STEPI), Korea
o (2017~2018) Director, Industry and Academic Cooperation Foundation, KNU, Korea
o (2019~present) Director, Laboratory Animal Resources in KNU, Daegu, Korea
o (2008~2009) Visiting Professor, Graduate School of Medicine, University of Tokyo, Japan
o (2019~present) Director, Laboratory Animal Resources in KNU, Korea
o (1998~1999) Instructor, Massachusetts Medical School, USA
o (1996~1998) Postdoctoral Researcher, Massachusetts Medical School, USA
o (2018~2021) Advisory board member, Science and Technology Policy Institute (STEPI), Korea
o (2017~2018) Director, Industry and Academic Cooperation Foundation, KNU, Korea
o (2019~present) Director, Laboratory Animal Resources in KNU, Daegu, Korea
o (2008~2009) Visiting Professor, Graduate School of Medicine, University of Tokyo, Japan
o (2019~present) Director, Laboratory Animal Resources in KNU, Korea
o (1998~1999) Instructor, Massachusetts Medical School, USA
o (1996~1998) Postdoctoral Researcher, Massachusetts Medical School, USA
Research Interests
Osteoarthritis,
Osteoporosis,
Vascular Calcification,
Bone Cell Biology,
Biomineralization,
Runx/Cbfb transcription factors,
Mouse genetics
Osteoporosis,
Vascular Calcification,
Bone Cell Biology,
Biomineralization,
Runx/Cbfb transcription factors,
Mouse genetics
Major Research Achievements
o Essential roles for Cbfb in osteoblast formation and chondrocyte maturation by Runx2 and in articular chondrocyte maintenance by Runx1.
o Various biological applications of 4-Hexylresorcinol, including anticancer, anti-inflammatory, and biocompatibility enhancing functions.
o Establishment of a mouse vascular calcification (VC) model using high dose vitamin D and identifying the essential role of Runx2 and VDR in VC.
o Essential role of the Runx2 carboxyl terminus for subnuclear targeting, osteoblast formation, and chondrocyte maturation during skeletal tissue development
o Various biological applications of 4-Hexylresorcinol, including anticancer, anti-inflammatory, and biocompatibility enhancing functions.
o Establishment of a mouse vascular calcification (VC) model using high dose vitamin D and identifying the essential role of Runx2 and VDR in VC.
o Essential role of the Runx2 carboxyl terminus for subnuclear targeting, osteoblast formation, and chondrocyte maturation during skeletal tissue development
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Collaborations and top research areas from the last five years
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Excitatory neuron-specific core binding factor β (Cbfβ) deletion causes sex-independent spatial memory deficits and female-specific anxiety and depression-like behaviors in mice
Cui, Y., Kim, J. H., Kwon, J., Choi, P. R., Lee, K. M., Jin, X., Lee, D. K., Che, X., Kim, H. J., Suk, K. & Choi, J. Y., 14 Nov 2025, In: Biochemical and Biophysical Research Communications. 789, 152838.Research output: Contribution to journal › Article › peer-review
Open Access -
Phospholipase C β4 promotes RANKL-dependent osteoclastogenesis by interacting with MKK3 and p38 MAPK
Lee, D. K., Jin, X., Choi, P. R., Cui, Y., Che, X., Lee, S., Hur, K., Kim, H. J. & Choi, J. Y., Feb 2025, In: Experimental and Molecular Medicine. 57, 2, p. 323-334 12 p., 45964.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Sericin’s Potential in Osteoporosis Management: The Roles of L-Serine and D-Serine in Bone Metabolism Regulation
Kim, J. Y., Che, X., Kim, S., Choi, J., Lee, J. H., Lee, J. H., Kweon, H. Y., Lee, S. K., Choi, J. Y. & Kim, S. G., Feb 2025, In: Nutrients. 17, 3, 574.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The Application of L-Serine-Incorporated Gelatin Sponge into the Calvarial Defect of the Ovariectomized Rats
Lee, Y. J., Oh, J. H., Park, S., Choi, J., Hong, M. H., Kweon, H. Y., Chae, W. S., Che, X., Choi, J. Y. & Kim, S. G., Jan 2025, In: Tissue Engineering and Regenerative Medicine. 22, 1, p. 91-104 14 p., 106148.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
4-Hexylresorcinol Enhances Glut4 Expression and Glucose Homeostasis via AMPK Activation and Histone H3 Acetylation
Che, X., Oh, J. H., Kang, Y. J., Kim, D. W., Kim, S. G., Choi, J. Y. & Garagiola, U., Nov 2024, In: International Journal of Molecular Sciences. 25, 22, 12281.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations