장정호 교수(사범대학 생물교육과)

o (2001) B.S., Dept. Genetic Engineering, Kyungpook National University
o (2008) Ph.D. Dept. Life Science, POSTECH

o (2023~Present) Professor, Dept. of Biology education, Kyungpook National University, Daegu, Korea
o (2019~2020) Visiting Associate Professor, Dept. of Biophysics, University of Texas Southwestern Medical Center, Dallas, USA
o (2018~2023) Associate Professor, Dept. of Biology education, Kyungpook National University, Daegu, Korea
o (2013~2018) Assistant Professor, Dept. of Biology education, Kyungpook National University, Daegu, Korea
o (2009~2013) Postdoctoral Researcher, Dept. of Biological Sciences, Columbia University, New York, USA
o (2008~2009) Postdoctoral Researcher, Structural Biology Center, POSTECH, Pohang, Korea

Structural Biology, Molecular Biology, Biochemistry, Crystallography, Gene expression, RNA metabolism, DNA damage repair, Protein engineering,

o ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nat Commun. 14;14(1):8341
o Structural and functional studies of mammalian DXO reveals role in pre-mRNA 5´-end quality control and link of capping to pre-mRNA processing. Mol. Cell 50(1): 104-115
o Dxo1 is a new type of eukaryotic enzyme with both decapping and 5′-3′ exoribonuclease activity. Nat. Struct. Mol. Biol. 19(10): 1011-1017
o Structural and biochemical studies of the 5’-3’ exoribonuclease Xrn1. Nat. Struct. Mol. Biol. 18(3): 270-276
o Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase. Mol. Cell 41(3): 311-320
o Crystal structure of the eIF4A-PDCD4 complex: insight into the inhibition of translation. Proc. Natl. Acad. Sci. U.S.A.106(9): 3148-3153
o Crystal structure of the Mus81-Eme1 complex. Genes & Dev. 22; 1093-1106

https://sites.google.com/site/knumolbio