Personal profile
In Korean
허근 교수(의과대학 의학과)
Education
o (2001) B.S., Sungkyunkwan University College of Life Science, Seoul, Korea
o (2004) M.S., Seoul National University College of Medicine, Seoul, Korea
o (2008) Ph.D., Seoul National University College of Medicine, Seoul, Korea
o (2004) M.S., Seoul National University College of Medicine, Seoul, Korea
o (2008) Ph.D., Seoul National University College of Medicine, Seoul, Korea
Professional Experience
o (2019~Present) Associate Professor, School of Medicine, Kyungpook National University, Daegu, Korea
o (2022~Present) Secretary General, Faculty Assembly, Kyungpook National University, Daegu, Korea
o (2019~2020) Vice Dean of Strategy, Division of Planning and Coordination, Office of Planning, Kyungpook National University, Daegu, Korea
o (2014~2019) Assistant Professor, School of Medicine, Kyungpook National University, Daegu, Korea
o (2013~2014) Senior Researcher, Korea Research Institute Bioscience and Biotechnology (KRIBB), Daejeon, Korea
o (2010~2013) Postdoctoral Research Fellow, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, United States
o (2008~2010) Postdoctoral Research Fellow, National Cancer Center Research Institute, Tokyo, Japan
o (2008~2008) Senior Research Fellow, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
o (2022~Present) Secretary General, Faculty Assembly, Kyungpook National University, Daegu, Korea
o (2019~2020) Vice Dean of Strategy, Division of Planning and Coordination, Office of Planning, Kyungpook National University, Daegu, Korea
o (2014~2019) Assistant Professor, School of Medicine, Kyungpook National University, Daegu, Korea
o (2013~2014) Senior Researcher, Korea Research Institute Bioscience and Biotechnology (KRIBB), Daejeon, Korea
o (2010~2013) Postdoctoral Research Fellow, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, United States
o (2008~2010) Postdoctoral Research Fellow, National Cancer Center Research Institute, Tokyo, Japan
o (2008~2008) Senior Research Fellow, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Research Interests
Cancer (Colorectal cancer, Gastric cancer, and Hepatocellular carcinoma),
Metastasis,
Organoids,
Inflammation,
Carcinogenesis,
Cancer Biomarker,
Liquid Biopsy,
Epigenetics(Methylation and Histone modification),
Non-coding RNAs(microRNA, lncRNA, circRNA),
Exosome, Animal model
Metastasis,
Organoids,
Inflammation,
Carcinogenesis,
Cancer Biomarker,
Liquid Biopsy,
Epigenetics(Methylation and Histone modification),
Non-coding RNAs(microRNA, lncRNA, circRNA),
Exosome, Animal model
Major Research Achievements
o MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. Gut. Sep 2013;62(9):1315-1326.
o Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis. Gut. Apr 2014;63(4):635-646.
o MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1. Gut. Feb 2015;64(2):203-214.
o Identification of a metastasis-specific MicroRNA signature in human colorectal cancer. Journal of the National Cancer Institute. Mar 2015;107(3).
o Circulating microRNA-203 predicts prognosis and metastasis in human colorectal cancer. Gut. Apr 2017;66(4):654-665.
o Epigenetic regulation of SMAD3 by histone methyltransferase SMYD2 promotes lung cancer metastasis. Exp Mol Med. May 1 2023.
o Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis. Gut. Apr 2014;63(4):635-646.
o MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1. Gut. Feb 2015;64(2):203-214.
o Identification of a metastasis-specific MicroRNA signature in human colorectal cancer. Journal of the National Cancer Institute. Mar 2015;107(3).
o Circulating microRNA-203 predicts prognosis and metastasis in human colorectal cancer. Gut. Apr 2017;66(4):654-665.
o Epigenetic regulation of SMAD3 by histone methyltransferase SMYD2 promotes lung cancer metastasis. Exp Mol Med. May 1 2023.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A serum exosomal microRNA-based artificial intelligence diagnostic model for highly accurate detection of hepatocellular carcinoma
Hwang, J. S., Lee, S., Kim, G., Jeong, H., Kwon, K., Jung, E., Roh, Y., Son, T., Lee, H., Lee, M. S., Oh, K. J., Lee, H. W., Lee, Y. R., Park, S. Y., Tak, W. Y., Ban, H. S., Cho, H. S., Son, M. Y., Kim, J. S. & Hur, K. & 2 others, , Sep 2025, In: Cancer Communications. 45, 9, p. 1188-1193 6 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Helicobacter pylori VacA-induced mitochondrial damage in the gastric pit cells of the antrum and therapeutic rescue
Son, Y. S., Kwon, Y. H., Lee, M. S., Kwon, O., Jeong, Y. J., Mun, S. J., Jeon, S., Park, J. H., Han, M. H., Bae, J. S., Hur, K., Jang, A. R., Park, J. H., Cho, H. S., Jung, C. R., Ryu, C. M., Son, M. J., Park, D. S. & Son, M. Y., Mar 2025, In: Biomaterials. 314, 122842.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
MicroRNA-135b-5p Is a Pathologic Biomarker in the Endothelial Cells of Arteriovenous Malformations
Lee, J. S., Kim, G., Lee, J. H., Ryu, J. Y., Oh, E. J., Kim, H. M., Kwak, S., Hur, K. & Chung, H. Y., May 2024, In: International Journal of Molecular Sciences. 25, 9, 4888.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Positive regulation of cell proliferation by the miR-1290-EHHADH axis in hepatocellular carcinoma
Lee, J., Kim, G., Han, T. S., Jung, E., Son, T., Kim, K., Kwon, K., Roh, Y., Ryu, T. Y., Tae, I. H., Kang, Y., Lee, B., Lee, Y. R., Park, S. Y., Tak, W. Y., Kim, D. S., Son, M. Y., Hur, K. & Cho, H. S., Jun 2024, In: Cancer Communications. 44, 6, p. 705-709 5 p.Research output: Contribution to journal › Letter › peer-review
Open Access5 Scopus citations -
Epigenetic regulation of SMAD3 by histone methyltransferase SMYD2 promotes lung cancer metastasis
Kim, K., Ryu, T. Y., Jung, E., Han, T. S., Lee, J., Kim, S. K., Roh, Y. N., Lee, M. S., Jung, C. R., Lim, J. H., Hamamoto, R., Lee, H. W., Hur, K., Son, M. Y., Kim, D. S. & Cho, H. S., May 2023, In: Experimental and Molecular Medicine. 55, 5, p. 952-964 13 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations