Research output per year
Research output per year
Personal profile
In Korean
권오신 교수(자연과학대학 생명공학부)
Education
o (1983) B.A., Kyungpook National University
o (1985) M.A., Kyungpook National University
o (1993) Ph.D., University of Tennessee, Knoxville, USA
o (1985) M.A., Kyungpook National University
o (1993) Ph.D., University of Tennessee, Knoxville, USA
Professional Experience
o (2006~Present) Professor, Kyungpook National University
o (2008~Present) Editor, BMB Report
o (2012~2015) Member of Review Board, National Research Foundation of Korea
o (2006~2007) Editor, Journal of biochemistry and molecular biology (JBMB)
o (2001~2005) Associate Professor, Kyungpook National University
o (1997~2000) Assistant Professor, Kyungpook National University
o (1998) Visiting professor, University of Tennessee, Knoxville, USA
o (1995~1996) Lecturer, Kyungpook National University
o (1994~1995) Postdoctoral Researcher, Harvard University, Massachusetts, U.S.A.
o (2008~Present) Editor, BMB Report
o (2012~2015) Member of Review Board, National Research Foundation of Korea
o (2006~2007) Editor, Journal of biochemistry and molecular biology (JBMB)
o (2001~2005) Associate Professor, Kyungpook National University
o (1997~2000) Assistant Professor, Kyungpook National University
o (1998) Visiting professor, University of Tennessee, Knoxville, USA
o (1995~1996) Lecturer, Kyungpook National University
o (1994~1995) Postdoctoral Researcher, Harvard University, Massachusetts, U.S.A.
Research Interests
Proteomics, Biomarker Exploration, Cancer research, Combination drug therapy, Post-transcriptional modification (PTM), GlcNAcylation, Mouse Xenograft, Vitamin B6 metabolism, PLP Kinase, PLP phosphatase, Epilepsy
Major Research Achievements
o Development of anti-cancer combined treatment
o Cell death mechanism through regulation of GlcNAcylation in cancer cells
o Proteomic analysis of marker proteins associated with steatohepatitis, alcoholic liver disease, and liver fibrosis
o Development of an anti-epilepsy drug::PL-GABA
o Genomic organization/Recombinantion of human pyridoxine 5′‐phosphate oxidase and pyridoxal kinase
o Molecular cloning of Human pyridoxal phosphatase and 4-aminobutyrate aminotransferase
o Reversible unfolding monitored by fluorescence and phosphorescence spectroscopy
o Cell death mechanism through regulation of GlcNAcylation in cancer cells
o Proteomic analysis of marker proteins associated with steatohepatitis, alcoholic liver disease, and liver fibrosis
o Development of an anti-epilepsy drug::PL-GABA
o Genomic organization/Recombinantion of human pyridoxine 5′‐phosphate oxidase and pyridoxal kinase
o Molecular cloning of Human pyridoxal phosphatase and 4-aminobutyrate aminotransferase
o Reversible unfolding monitored by fluorescence and phosphorescence spectroscopy
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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Protective effects of cell permeable Tat-PIM2 protein on oxidative stress induced dopaminergic neuronal cell death
Shin, M. J., Eum, W. S., Youn, G. S., Park, J. H., Yeo, H. J., Yeo, E. J., Kwon, H. J., Sohn, E. J., Lee, L. R., Kim, N. Y., Kwon, S. Y., Kim, S. M., Jung, H. Y., Kim, D. S., Cho, S. W., Kwon, O. S., Kim, D. W. & Choi, S. Y., May 2023, In: Heliyon. 9, 5, e15945.Research output: Contribution to journal › Article › peer-review
Open Access -
Synergistic apoptosis by combination of metformin and an O-GlcNAcylation inhibitor in colon cancer cells
Lee, D. E., Lee, G. Y., Lee, H. M., Choi, S. Y., Lee, S. J. & Kwon, O. S., Dec 2023, In: Cancer Cell International. 23, 1, 108.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Tat-GSTpi Inhibits Dopaminergic Cells against MPP+-Induced Cellular Damage via the Reduction of Oxidative Stress and MAPK Activation
Choi, Y. J., Yeo, H. J., Shin, M. J., Youn, G. S., Park, J. H., Yeo, E. J., Kwon, H. J., Lee, L. R., Kim, N. Y., Kwon, S. Y., Kim, S. M., Kim, D. W., Jung, H. Y., Kwon, O. S., Lee, C. H., Park, J. K., Lee, K. W., Han, K. H., Park, J. & Eum, W. S. & 1 others, , Mar 2023, In: Biomedicines. 11, 3, 836.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Tat-RAN attenuates brain ischemic injury in hippocampal HT-22 cells and ischemia animal model
Yeo, E. J., Shin, M. J., Youn, G. S., Park, J. H., Yeo, H. J., Kwon, H. J., Lee, L. R., Kim, N. Y., Kwon, S. Y., Kim, S. M., Lee, J., Lee, K. W., Lee, C. H., Cho, Y. J., Kwon, O. S., Kim, D. W., Jung, H. Y., Eum, W. S. & Choi, S. Y., Jul 2023, In: Neurochemistry International. 167, 105538.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Tat-Thioredoxin-like protein 1 attenuates ischemic brain injury by regulation of MAPKs and apoptosis signaling
Cha, H. J., Eum, W. S., Youn, G. S., Park, J. H., Yeo, H. J., Yeo, E. J., Kwon, H. J., Lee, L. R., Kim, N. Y., Kwon, S. Y., Cho, Y. J., Cho, S. W., Kwon, O. S., Sohn, E. J., Kim, D. W., Kim, D. S., Lee, Y. R., Shin, M. J. & Choi, S. Y., 2023, In: BMB Reports. 56, 4, p. 234-239 6 p.Research output: Contribution to journal › Article › peer-review
Open Access