Personal profile
In Korean
박낭운 교수(의과대학 의학과)
Education
o (1986) B.Sc., School of Medicine, Kyungpook National University
o (1988) M.Sc., School of Medicine, Kyungpook National University
o (1991) Ph.D., Kyungpook National University
o (1988) M.Sc., School of Medicine, Kyungpook National University
o (1991) Ph.D., Kyungpook National University
Professional Experience
o (1996~Present) Assistant Professor, Associate Professor, Professor, Department of Biochemistry, School of Medicine, Kyungpook National University, Daegu
o (1994~1996) Postdoctoral Fellow, Deparment of Molecular Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA
o (1994~1996) Postdoctoral Fellow, Deparment of Molecular Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA
Research Interests
Development and application of elastin-like polypeptide (ELP)-based drug delivery system
Molecular imaging and targeted therapy of tumors using nanoparticles decorated with tumor-specific homing peptides
Targeting tumor microenvironment
Molecular imaging and targeted therapy of tumors using nanoparticles decorated with tumor-specific homing peptides
Targeting tumor microenvironment
Major Research Achievements
o Multivalent targeting based delivery of therapeutic peptide using AP1-ELP carrier for effective cancer therapy
o Application of Bld-1-embedded elastin-like polypeptides in tumor targeting
o Development of elastin-like polypeptide for targeted specific gene delivery in vivo
o Therapeutic effect of IL-4 receptor-targeting pro-apoptotic peptide (AP1-ELP-KLAK) in glioblastoma tumor model
o Application of Bld-1-embedded elastin-like polypeptides in tumor targeting
o Development of elastin-like polypeptide for targeted specific gene delivery in vivo
o Therapeutic effect of IL-4 receptor-targeting pro-apoptotic peptide (AP1-ELP-KLAK) in glioblastoma tumor model
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Strategic Optimization of Nanoparticle Characteristics to Enhance Tumor Targeting and Doxorubicin Delivery
Lee, Y. J., Hong, J., Seo, B. Y., Lee, B. H., Sarangthem, V. & Park, R. W., 2025, In: International Journal of Nanomedicine. 20, p. 6357-6378 22 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Immune Checkpoint-Blocking Nanocages Cross the Blood-Brain Barrier and Impede Brain Tumor Growth
Kim, M., Yoon, H. J., Lee, C., Lee, M., Park, R. W., Lee, B., Park, E. J. & Kim, S., 8 Jan 2024, In: ACS Biomaterials Science and Engineering. 10, 1, p. 575-587 13 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Multifunctional elastin-like polypeptide nanocarriers for efficient miRNA delivery in cancer therapy
Hong, J., Sim, D., Lee, B. H., Sarangthem, V. & Park, R. W., Dec 2024, In: Journal of Nanobiotechnology. 22, 1, 293.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Dual Impact of IGF2 on Alveolar Stem Cell Function during Tobacco-Induced Injury Repair and Development of Pulmonary Emphysema and Cancer
Boo, H. J., Min, H. Y., Park, C. S., Park, J. S., Jeong, J. Y., Lee, S. Y., Kim, W. Y., Lee, J. W., Oh, S. R., Park, R. W. & Lee, H. Y., 2 Jun 2023, In: Cancer Research. 83, 11, p. 1782-1799 18 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse
Cho, J., Min, H. Y., Lee, H. J., Hyun, S. Y., Sim, J. Y., Noh, M., Hwang, S. J., Park, S. H., Boo, H. J., Lee, H. J., Hong, S., Park, R. W., Shin, Y. K., Hung, M. C. & Lee, H. Y., 15 May 2023, In: Journal of Clinical Investigation. 133, 10Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations