Personal profile
In Korean
홍연철 교수(의과대학 의학과)
Education
o (1994) B.S., Kyungpook National University, Daegu
o (1996) M.Sc., Kyungpook National University, Daegu
o (2006) Ph.D., Osaka University, Osaka, Japan
o (1996) M.Sc., Kyungpook National University, Daegu
o (2006) Ph.D., Osaka University, Osaka, Japan
Professional Experience
o (2007~Present) Professor, Kyungpook National University, Daegu
o (2006~2007) Postdoctoral Researcher, Research Institute for Microbial Diseases (RIMD), Osaka, Japan
o (1998~2001) Research Assistant, Kyungpook National University, Daegu
o (1995~1998) Researcher, Mogam Biotechnology Research Institute (MBRI), Seoul
o (2006~2007) Postdoctoral Researcher, Research Institute for Microbial Diseases (RIMD), Osaka, Japan
o (1998~2001) Research Assistant, Kyungpook National University, Daegu
o (1995~1998) Researcher, Mogam Biotechnology Research Institute (MBRI), Seoul
Research Interests
Development of diagnostics and therapeutics for pathogenic protozoa
Development of diagnostics and therapeutics for protozoa causing amoebic encephalitis
Development of methods for Acanthamoeba gene manipulation
Elucidation of the amoeba encystment mechanism
Development of diagnostics and therapeutics for protozoa causing amoebic encephalitis
Development of methods for Acanthamoeba gene manipulation
Elucidation of the amoeba encystment mechanism
Major Research Achievements
o Elucidation that autophagy is involved in Acanthamoeba encystment
o Identification of essential factors related to Acanthamoeba encystment
o Development of a diagnostic method for Acanthamoeba using LAMP and multiplex PCR
o Development of a diagnostic method for Trichomoniasis using the LAMP method
o Identification of essential factors related to Acanthamoeba encystment
o Development of a diagnostic method for Acanthamoeba using LAMP and multiplex PCR
o Development of a diagnostic method for Trichomoniasis using the LAMP method
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Collaborations and top research areas from the last five years
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(‒)-Epicatechin enhances the anti-Acanthamoeba activity of chlorhexidine through synergistic action
Lê, H. G., Võ, T. C., Nguyễn, T. H., Cho, M., Hong, Y., Yu, H. S. & Na, B. K., Mar 2026, In: Acta Tropica. 275, 108010.Research output: Contribution to journal › Article › peer-review
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A xanthone O-glucoside isolated from Iris setosa Pall. ex Link exhibits promising anti-amoebic activity against the brain-eating amoeba Naegleria fowleri
Lê, H. G., Hwang, B. S., Choi, J. S., Jeong, Y. T., Võ, T. C., Cho, M., Hong, Y., Kim, J. H., Oh, Y. T. & Na, B. K., Nov 2025, In: Phytomedicine. 147, 157199.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Establishing a Cre/loxP-based genetic manipulation system for Acanthamoeba: Targeted genome editing and stable reporter expression
Aung, J. M., Joo, S. Y., Na, B. K., Bang, S., Shin, M., Goo, Y. K. & Hong, Y., 1 Feb 2025, In: Parasites, Hosts and Diseases. 63, 1, p. 25-36 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification and characterization of a DNA-binding protein from starved cells (Dps) homologue in Acanthamoeba: Implications for encystment-induced DNA protection
Bang, S., Joo, S. Y., Aung, J. M., Lee, J. C., Na, B. K., Hong, Y. & Shin, M., Nov 2025, In: Acta Tropica. 271, 107837.Research output: Contribution to journal › Article › peer-review
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(‒)-Epicatechin reveals amoebicidal activity against Acanthamoeba castellanii by activating the programmed cell death pathway
Lê, H. G., Kang, J. M., Võ, T. C., Yoo, W. G., Hong, Y. & Na, B. K., Mar 2024, In: Phytomedicine. 125, 155389.Research output: Contribution to journal › Article › peer-review
5 Scopus citations