Personal profile
In Korean
부용출 교수(의과대학 의학과)
Education
o (1999) Ph.D., Seoul National University, Seoul, Korea.
o (1992) M.S., Seoul National University, Seoul, Korea
o (1987) B.A., Seoul National University, Seoul, Korea
o (1992) M.S., Seoul National University, Seoul, Korea
o (1987) B.A., Seoul National University, Seoul, Korea
Professional Experience
o (2021~2023) Associate Dean of Research, School of Medicine, Kyungpook National University, Daegu, Korea
o (2021~2023) Chair, Department of Biomedical Science, The Graduate School, Kyungpook National University, Daegu, Korea
o (2016~2021) Chair, Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
o (2014~present) Professor, Department of Molecular Medicine, Kyungpook National University School of Medicine, Daegu, Korea
o (2009~2014) Associate Professor, Department of Molecular Medicine, Kyungpook National University School of Medicine, Daegu, Korea
o (2005~2009) Assistant Professor, Department of Molecular Medicine, Kyungpook National University School of Medicine, Daegu, Korea
o (2003~2005) Senior Researcher, Jeju Technopark, Jeju, Korea
o (2000~2003) Postdoctoral Fellow, Georgia Institute of Technology/Emory University, Atlanta, GA, USA
o (1999~2000) Postdoctoral Fellow, University of Alabama at Birmingham, Birmingham, AL, USA
o (1987~1995) Senior Researcher, Amore Pacific, Seoul, Korea
o (2021~2023) Chair, Department of Biomedical Science, The Graduate School, Kyungpook National University, Daegu, Korea
o (2016~2021) Chair, Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
o (2014~present) Professor, Department of Molecular Medicine, Kyungpook National University School of Medicine, Daegu, Korea
o (2009~2014) Associate Professor, Department of Molecular Medicine, Kyungpook National University School of Medicine, Daegu, Korea
o (2005~2009) Assistant Professor, Department of Molecular Medicine, Kyungpook National University School of Medicine, Daegu, Korea
o (2003~2005) Senior Researcher, Jeju Technopark, Jeju, Korea
o (2000~2003) Postdoctoral Fellow, Georgia Institute of Technology/Emory University, Atlanta, GA, USA
o (1999~2000) Postdoctoral Fellow, University of Alabama at Birmingham, Birmingham, AL, USA
o (1987~1995) Senior Researcher, Amore Pacific, Seoul, Korea
Research Interests
His research activities are directed toward the identification of therapeutic targets and development of intervention strategies for age-related diseases. He is interested in natural antioxidants, bioactive peptides, and epigenedtic drugs for their application in cosmetology, dermatology, vascular biology, etc. His teaching disciplines include Biochemistry, Molecular Biology, Cell biology, Redox biology, etc.
Major Research Achievements
oBoo, Y.C. Insights into How Plant-Derived Extracts and Compounds Can Help in the Prevention and Treatment of Keloid Disease: Established and Emerging Therapeutic Targets. International Journal of Molecular Sciences. 2024, 25, 1235. https://doi.org/10.3390/ijms25021235.
oHa JW, Choi JY, Boo YC. Differential Effects of Histidine and Histidinamide versus Cysteine and Cysteinamide on Copper Ion-Induced Oxidative Stress and Cytotoxicity in HaCaT Keratinocytes. Antioxidants (Basel). 2023 Mar 25;12(4):801. doi: 10.3390/antiox12040801.
oLee JE, Boo YC. Combination of Glycinamide and Ascorbic Acid Synergistically Promotes Collagen Production and Wound Healing in Human Dermal Fibroblasts. Biomedicines. 2022 Apr 29;10(5):1029. doi: 10.3390/biomedicines10051029.
oLee HK, Ha JW, Hwang YJ, Boo YC. Identification of L-Cysteinamide as a Potent Inhibitor of Tyrosinase-Mediated Dopachrome Formation and Eumelanin Synthesis. Antioxidants (Basel). 2021 Jul 27;10(8):1202. doi: 10.3390/antiox10081202.
oSong H, Hwang YJ, Ha JW, Boo YC. Screening of an Epigenetic Drug Library Identifies 4-((hydroxyamino)carbonyl)-N-(2-hydroxyethyl)-N-Phenyl-Benzeneacetamide that Reduces Melanin Synthesis by Inhibiting Tyrosinase Activity Independently of Epigenetic Mechanisms. Int J Mol Sci. 2020 Jun 28;21(13):4589. doi: 10.3390/ijms21134589.
oKim JH, Seok JK, Kim YM, Boo YC. Identification of small peptides and glycinamide that inhibit melanin synthesis using a positional scanning synthetic peptide combinatorial library. British Journal of Dermatology. 2019 Jul;181(1):128-137. doi:10.1111/bjd.17634.
oHa JW, Choi JY, Boo YC. Differential Effects of Histidine and Histidinamide versus Cysteine and Cysteinamide on Copper Ion-Induced Oxidative Stress and Cytotoxicity in HaCaT Keratinocytes. Antioxidants (Basel). 2023 Mar 25;12(4):801. doi: 10.3390/antiox12040801.
oLee JE, Boo YC. Combination of Glycinamide and Ascorbic Acid Synergistically Promotes Collagen Production and Wound Healing in Human Dermal Fibroblasts. Biomedicines. 2022 Apr 29;10(5):1029. doi: 10.3390/biomedicines10051029.
oLee HK, Ha JW, Hwang YJ, Boo YC. Identification of L-Cysteinamide as a Potent Inhibitor of Tyrosinase-Mediated Dopachrome Formation and Eumelanin Synthesis. Antioxidants (Basel). 2021 Jul 27;10(8):1202. doi: 10.3390/antiox10081202.
oSong H, Hwang YJ, Ha JW, Boo YC. Screening of an Epigenetic Drug Library Identifies 4-((hydroxyamino)carbonyl)-N-(2-hydroxyethyl)-N-Phenyl-Benzeneacetamide that Reduces Melanin Synthesis by Inhibiting Tyrosinase Activity Independently of Epigenetic Mechanisms. Int J Mol Sci. 2020 Jun 28;21(13):4589. doi: 10.3390/ijms21134589.
oKim JH, Seok JK, Kim YM, Boo YC. Identification of small peptides and glycinamide that inhibit melanin synthesis using a positional scanning synthetic peptide combinatorial library. British Journal of Dermatology. 2019 Jul;181(1):128-137. doi:10.1111/bjd.17634.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Restoring Glutathione Homeostasis in Glycation-Related Eye Diseases: Mechanistic Insights and Therapeutic Interventions Beyond VEGF Inhibition
Boo, Y. C., Jun 2025, In: Antioxidants. 14, 6, 731.Research output: Contribution to journal › Review article › peer-review
Open Access4 Scopus citations -
Synthetic and Natural Agents Targeting Advanced Glycation End-Products for Skin Anti-Aging: A Comprehensive Review of Experimental and Clinical Studies
Choi, J. Y., Ha, N. G., Lee, W. J. & Boo, Y. C., Apr 2025, In: Antioxidants. 14, 4, 498.Research output: Contribution to journal › Review article › peer-review
Open Access10 Scopus citations -
A Spectrophotometric Method to Determine Minimal Erythema Dose for Ultraviolet Radiation in Human Skin
Lee, E. J., Lee, C. H., Baek, J. H., Koh, J. S. & Boo, Y. C., Nov 2024, In: Biomedicines. 12, 11, 2544.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth? A Review Comparing Their Therapeutic Efficacies, Phytochemical Components, and Modulatory Targets
Choi, J. Y., Boo, M. Y. & Boo, Y. C., May 2024, In: Molecules. 29, 10, 2288.Research output: Contribution to journal › Review article › peer-review
Open Access43 Scopus citations -
Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model
Nam, S. H., Kim, J. A., Lim, S., Lee, S. J., Kim, C. H., Bae, J. S., Boo, Y. C., Kim, Y. J. & Park, E. K., Oct 2024, In: Tissue Engineering and Regenerative Medicine. 21, 7, p. 1093-1107 15 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations