소독제를 탑재한 키토산 마이크로 비드 정밀 제조공정과 살 바이러스 효능평가

This study examines the efficiency of chitosan microbeads in manufacturing and their effectiveness as a disinfectant. The microbeads are developed using a solvent-assisted extraction process. The manufacturing process involves crosslinking chitosan through an emulsion-based method, with the help of a crosslinker. This leads to an increase in particle size while maintaining homogeneity and dispersion. The solvent-assisted method, which utilizes acetone, effectively extracts the crosslinked beads into the aqueous phase. This extraction process ensures the structural stability of the beads, with an average particle size of 40±3.94 µm. By incorporating the disinfectant agent into the chitosan beads, antiviral effects against the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) were observed. These effects were found to be effective at dilutions estimated to be between 1: 1 and 1: 100. The findings of this study demonstrate the inherent antiviral capabilities of chitosan beads and the enhanced impact when combined with the disinfectant. This suggests a synergistic approach to managing viral infections in livestock environments.