3D multi-functional neural probe array for mapping functional connectivities in a 3D neuron chip

Hyogeun Shin, Sohyun Kim, Nakwon Choi, Hyunjoo Jenny Lee, Eui Sung Yoon, Il Joo Cho

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

We present the first 3D multi-functional neural probe array integrated with optical, chemical, and electrical stimulation capabilities, developed for mapping the 3D functional connectivities among neurons cultured in a 3D hydrogel neuron chip. The proposed device is not only capable of stimulating neurons with various modalities but also tracking the propagated neural activities in the whole 3D hydrogel chip using the 3D electrode array. Using our 3D multi-functional neural probe array, we demonstrated successful in vitro experiments by electrically and chemically modulating neurons and recording neural signals on cultured neurons in the 3D hydrogel neuron chip.

Original languageEnglish
Title of host publicationMEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages321-324
Number of pages4
ISBN (Electronic)9781509019731
DOIs
StatePublished - 26 Feb 2016
Event29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016 - Shanghai, China
Duration: 24 Jan 201628 Jan 2016

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume2016-February
ISSN (Print)1084-6999

Conference

Conference29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016
Country/TerritoryChina
CityShanghai
Period24/01/1628/01/16

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