A case of primary small cell carcinoma in the common bile duct

Hea Won Park, Sang Hyuck Seo, Byoung Kuk Jang, Jun Young Hwang, Kyung Sik Park, Kwang Bum Cho, Jae Seok Hwang, Sung Hoon Ahn, Koo Jeong Kang, Y. N. Kang, Gab Chul Kim

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Extrapulmonary primary small cell carcinoma comprises approximately 4% of all small cell carcinoma. In the common bile duct, small cell carcinomas are extremely rare. We experienced a 60-year-old woman with small cell carcinoma arising in the common bile duct. Abdominal CT scan revealed an intraluminal mass in the proximal common bile duct and multiple lymphadenopathies. Microscopic examination of the tumor revealed proliferation of small monotonous anaplastic cells, which were characterized with hyperchromatic nuclei, high nuclear to cytoplasmic ratio, and frequent mitosis. By immunohistochemical stain, the tumor cells were strongly positive for chromogranin, synaptophysin, and CD56. We report this case with a review of literatures.

Original languageEnglish
Pages (from-to)260-263
Number of pages4
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume43
Issue number4
StatePublished - Apr 2004

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