A new route for isoquinolines catalyzed by palladium

Chan Sik Cho; Daksha B. Patel

doi:10.1016/j.molcata.2006.07.011

A new route for isoquinolines catalyzed by palladium

Chan Sik Cho, Daksha B. Patel

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

3-Bromopyridine-4-carbaldehyde is tethered with suitably electron withdrawing group substituted alkenes via Heck coupling followed by aldol reaction in dioxane at 150 °C under a catalytic system of Pd(OAc)₂/PPh₃/NaOAc to afford the corresponding isoquinolines in good yields.

Original language	English
Pages (from-to)	105-108
Number of pages	4
Journal	Journal of Molecular Catalysis A: Chemical
Volume	260
Issue number	1-2
DOIs	https://doi.org/10.1016/j.molcata.2006.07.011
State	Published - 15 Dec 2006

Keywords

3-Bromopyridine-4-carbaldehyde
Alkenes
Heck and aldol reactions
Isoquinolines
Palladium catalyst

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10.1016/j.molcata.2006.07.011

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title = "A new route for isoquinolines catalyzed by palladium",

abstract = "3-Bromopyridine-4-carbaldehyde is tethered with suitably electron withdrawing group substituted alkenes via Heck coupling followed by aldol reaction in dioxane at 150 °C under a catalytic system of Pd(OAc)2/PPh3/NaOAc to afford the corresponding isoquinolines in good yields.",

keywords = "3-Bromopyridine-4-carbaldehyde, Alkenes, Heck and aldol reactions, Isoquinolines, Palladium catalyst",

author = "Cho, {Chan Sik} and Patel, {Daksha B.}",

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AU - Patel, Daksha B.

PY - 2006/12/15

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N2 - 3-Bromopyridine-4-carbaldehyde is tethered with suitably electron withdrawing group substituted alkenes via Heck coupling followed by aldol reaction in dioxane at 150 °C under a catalytic system of Pd(OAc)2/PPh3/NaOAc to afford the corresponding isoquinolines in good yields.

AB - 3-Bromopyridine-4-carbaldehyde is tethered with suitably electron withdrawing group substituted alkenes via Heck coupling followed by aldol reaction in dioxane at 150 °C under a catalytic system of Pd(OAc)2/PPh3/NaOAc to afford the corresponding isoquinolines in good yields.

KW - 3-Bromopyridine-4-carbaldehyde

KW - Alkenes

KW - Heck and aldol reactions

KW - Isoquinolines

KW - Palladium catalyst

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DO - 10.1016/j.molcata.2006.07.011

M3 - Article

AN - SCOPUS:33750529137

SN - 1381-1169

VL - 260

SP - 105

EP - 108

JO - Journal of Molecular Catalysis A: Chemical

JF - Journal of Molecular Catalysis A: Chemical

IS - 1-2

ER -

A new route for isoquinolines catalyzed by palladium

Abstract

Keywords

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