Abstract
3-Bromopyridine-4-carbaldehyde is tethered with suitably electron withdrawing group substituted alkenes via Heck coupling followed by aldol reaction in dioxane at 150 °C under a catalytic system of Pd(OAc)2/PPh3/NaOAc to afford the corresponding isoquinolines in good yields.
| Original language | English |
|---|---|
| Pages (from-to) | 105-108 |
| Number of pages | 4 |
| Journal | Journal of Molecular Catalysis A: Chemical |
| Volume | 260 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - 15 Dec 2006 |
Keywords
- 3-Bromopyridine-4-carbaldehyde
- Alkenes
- Heck and aldol reactions
- Isoquinolines
- Palladium catalyst
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