A novel β-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages

Zhi Qiang Chang; Joong Su Lee; Mi Hyun Hwang; Joo Heon Hong; Hee Kyoung Jung; Sam Pin Lee; Seung Chun Park

doi:10.4142/jvs.2009.10.2.165

A novel β-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages

Zhi Qiang Chang
, Joong Su Lee
, Mi Hyun Hwang
, Joo Heon Hong
, Hee Kyoung Jung
, Sam Pin Lee
, Seung Chun Park

Department of Veterinary Medicine

Kyungpook National University
Bio Industry Center
Keimyung University

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

The effect of extracellular β-(1→3), (1→6)-glucan, produced by Paenibacillus polymyxa JB115, on nitric oxide (NO) production in RAW264.7 macrophages was investigated. β-glucan induced the production of NO by RAW264.7 macrophages in a concentration- and time-dependent manner. Moreover, β-glucan stimulation increased the mRNA expression of iNOS, COX-2 and IL-6 in RAW264.7 macrophages in a concentration-dependent manner.

Original language	English
Pages (from-to)	165-167
Number of pages	3
Journal	Journal of Veterinary Science
Volume	10
Issue number	2
DOIs	https://doi.org/10.4142/jvs.2009.10.2.165
State	Published - Jun 2009

Keywords

Macrophages
Nitric oxide
Paenibacillus polymyxa
β-Glucan

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10.4142/jvs.2009.10.2.165

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title = "A novel β-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages",

abstract = "The effect of extracellular β-(1→3), (1→6)-glucan, produced by Paenibacillus polymyxa JB115, on nitric oxide (NO) production in RAW264.7 macrophages was investigated. β-glucan induced the production of NO by RAW264.7 macrophages in a concentration- and time-dependent manner. Moreover, β-glucan stimulation increased the mRNA expression of iNOS, COX-2 and IL-6 in RAW264.7 macrophages in a concentration-dependent manner.",

keywords = "Macrophages, Nitric oxide, Paenibacillus polymyxa, β-Glucan",

author = "Chang, \{Zhi Qiang\} and Lee, \{Joong Su\} and Hwang, \{Mi Hyun\} and Hong, \{Joo Heon\} and Jung, \{Hee Kyoung\} and Lee, \{Sam Pin\} and Park, \{Seung Chun\}",

year = "2009",

month = jun,

doi = "10.4142/jvs.2009.10.2.165",

language = "English",

volume = "10",

pages = "165--167",

journal = "Journal of Veterinary Science",

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T1 - A novel β-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages

AU - Chang, Zhi Qiang

AU - Lee, Joong Su

AU - Hwang, Mi Hyun

AU - Hong, Joo Heon

AU - Jung, Hee Kyoung

AU - Lee, Sam Pin

AU - Park, Seung Chun

PY - 2009/6

Y1 - 2009/6

N2 - The effect of extracellular β-(1→3), (1→6)-glucan, produced by Paenibacillus polymyxa JB115, on nitric oxide (NO) production in RAW264.7 macrophages was investigated. β-glucan induced the production of NO by RAW264.7 macrophages in a concentration- and time-dependent manner. Moreover, β-glucan stimulation increased the mRNA expression of iNOS, COX-2 and IL-6 in RAW264.7 macrophages in a concentration-dependent manner.

AB - The effect of extracellular β-(1→3), (1→6)-glucan, produced by Paenibacillus polymyxa JB115, on nitric oxide (NO) production in RAW264.7 macrophages was investigated. β-glucan induced the production of NO by RAW264.7 macrophages in a concentration- and time-dependent manner. Moreover, β-glucan stimulation increased the mRNA expression of iNOS, COX-2 and IL-6 in RAW264.7 macrophages in a concentration-dependent manner.

KW - Macrophages

KW - Nitric oxide

KW - Paenibacillus polymyxa

KW - β-Glucan

UR - https://www.scopus.com/pages/publications/68949083445

U2 - 10.4142/jvs.2009.10.2.165

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SN - 1229-845X

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SP - 165

EP - 167

JO - Journal of Veterinary Science

JF - Journal of Veterinary Science

IS - 2

ER -

A novel β-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages

Abstract

Keywords

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