A novel COCH mutation associated with autosomal dominant nonsyndromic hearing loss disrupts the structural stability of the vWFA2 domain

Biochemistry, Genetics and Molecular Biology

• Autosomal Dominant Inheritance 100%
• Wild Type 50%
• Missense Mutation 50%
• Biochemical Analysis 50%
• Mammalian Cell 50%
• Cell Lysate 50%
• Disulfide 50%
• Western Blot 50%
• Immunocytochemistry 50%
• Golgi Apparatus 50%

Immunology and Microbiology

• Autosomal Dominant Inheritance 100%
• Western Blot 50%
• Cell Line 50%
• Endoplasmic reticulum 50%
• Cell Lysate 50%
• Golgi Complex 50%
• Missense Mutation 50%
• Wild Type 50%
• Immunocytochemistry 50%

Neuroscience

• Cochlin 100%
• Cell Line 14%
• Missense Mutation 14%
• Endoplasmic reticulum 14%
• Immunocytochemistry 14%
• Western Blot 14%