A pilot study investigating the effect of transcranial direct current stimulation on the electrophysiological correlates of working memory in patients with schizophrenia

Sun Young Moon; Minah Kim; Wu Jeong Hwang; Tae Young Lee; Jun Soo Kwon

doi:10.1016/j.pscychresns.2018.12.014

A pilot study investigating the effect of transcranial direct current stimulation on the electrophysiological correlates of working memory in patients with schizophrenia

Sun Young Moon, Minah Kim, Wu Jeong Hwang, Tae Young Lee, Jun Soo Kwon

Department of Medicine

Seoul National University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Transcranial direct current stimulation (tDCS) exerts pro-cognitive effects in various populations. We evaluated the effect of tDCS on cognitive performance and its electrophysiological correlates in schizophrenia patients. Ten participants received 10 sessions of tDCS and performed cognitive performance tasks; error-related negativity and correct response negativity (CRN) were measured before and after tDCS. Verbal performance was improved by tDCS and strongly correlated with a reduced CRN amplitude. Despite the lack of sham control design and possible practice effects of cognitive tasks, we might conclude that CRN could be a modifiable electrophysiological correlate of cognitive improvement by tDCS.

Original language	English
Pages (from-to)	9-12
Number of pages	4
Journal	Psychiatry Research - Neuroimaging
Volume	284
DOIs	https://doi.org/10.1016/j.pscychresns.2018.12.014
State	Published - 28 Feb 2019

Keywords

Correct response negativity (CRN)
Error-related negativity (ERN)
Event-related potential (ERP)
Transcranial direct current stimulation (tDCS)
Working memory

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.pscychresns.2018.12.014

Cite this

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title = "A pilot study investigating the effect of transcranial direct current stimulation on the electrophysiological correlates of working memory in patients with schizophrenia",

abstract = "Transcranial direct current stimulation (tDCS) exerts pro-cognitive effects in various populations. We evaluated the effect of tDCS on cognitive performance and its electrophysiological correlates in schizophrenia patients. Ten participants received 10 sessions of tDCS and performed cognitive performance tasks; error-related negativity and correct response negativity (CRN) were measured before and after tDCS. Verbal performance was improved by tDCS and strongly correlated with a reduced CRN amplitude. Despite the lack of sham control design and possible practice effects of cognitive tasks, we might conclude that CRN could be a modifiable electrophysiological correlate of cognitive improvement by tDCS.",

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AU - Kwon, Jun Soo

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KW - Error-related negativity (ERN)

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A pilot study investigating the effect of transcranial direct current stimulation on the electrophysiological correlates of working memory in patients with schizophrenia

Abstract

Keywords

UN SDGs

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