A two-photon fluorescent probe for lysosomal zinc ions

Hyo Jun Lee; Chang Woo Cho; Hyewon Seo; Subhankar Singha; Yong Woong Jun; Kyung Ha Lee; Youngseob Jung; Kyong Tai Kim; Seongjun Park; Sung Chul Bae; Kyo Han Ahn

doi:10.1039/c5cc06976a

A two-photon fluorescent probe for lysosomal zinc ions

Hyo Jun Lee
, Chang Woo Cho
, Hyewon Seo
, Subhankar Singha
, Yong Woong Jun
, Kyung Ha Lee
, Youngseob Jung
, Kyong Tai Kim
, Seongjun Park
, Sung Chul Bae
, Kyo Han Ahn

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

The selective detection of zinc ions in lysosomes over that in cytosol is achieved with a fluorescent probe, which enabled the fluorescence imaging of endogenous zinc ions in lysosomes of NIH 3T3 cells as well as mouse hippocampal tissues by two-photon microscopy under excitation at 900 nm.

Original language	English
Pages (from-to)	124-127
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	1
DOIs	https://doi.org/10.1039/c5cc06976a
State	Published - 2016

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10.1039/c5cc06976a

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title = "A two-photon fluorescent probe for lysosomal zinc ions",

abstract = "The selective detection of zinc ions in lysosomes over that in cytosol is achieved with a fluorescent probe, which enabled the fluorescence imaging of endogenous zinc ions in lysosomes of NIH 3T3 cells as well as mouse hippocampal tissues by two-photon microscopy under excitation at 900 nm.",

author = "Lee, \{Hyo Jun\} and Cho, \{Chang Woo\} and Hyewon Seo and Subhankar Singha and Jun, \{Yong Woong\} and Lee, \{Kyung Ha\} and Youngseob Jung and Kim, \{Kyong Tai\} and Seongjun Park and Bae, \{Sung Chul\} and Ahn, \{Kyo Han\}",

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year = "2016",

doi = "10.1039/c5cc06976a",

language = "English",

volume = "52",

pages = "124--127",

journal = "Chemical Communications",

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T1 - A two-photon fluorescent probe for lysosomal zinc ions

AU - Lee, Hyo Jun

AU - Cho, Chang Woo

AU - Seo, Hyewon

AU - Singha, Subhankar

AU - Jun, Yong Woong

AU - Lee, Kyung Ha

AU - Jung, Youngseob

AU - Kim, Kyong Tai

AU - Park, Seongjun

AU - Bae, Sung Chul

AU - Ahn, Kyo Han

PY - 2016

Y1 - 2016

N2 - The selective detection of zinc ions in lysosomes over that in cytosol is achieved with a fluorescent probe, which enabled the fluorescence imaging of endogenous zinc ions in lysosomes of NIH 3T3 cells as well as mouse hippocampal tissues by two-photon microscopy under excitation at 900 nm.

AB - The selective detection of zinc ions in lysosomes over that in cytosol is achieved with a fluorescent probe, which enabled the fluorescence imaging of endogenous zinc ions in lysosomes of NIH 3T3 cells as well as mouse hippocampal tissues by two-photon microscopy under excitation at 900 nm.

UR - https://www.scopus.com/pages/publications/84950259728

U2 - 10.1039/c5cc06976a

DO - 10.1039/c5cc06976a

M3 - Article

C2 - 26503088

AN - SCOPUS:84950259728

SN - 1359-7345

VL - 52

SP - 124

EP - 127

JO - Chemical Communications

JF - Chemical Communications

IS - 1

ER -

A two-photon fluorescent probe for lysosomal zinc ions

Abstract

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