Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL                         –/–                          mice

Evelyn Saba; Seung Hyung Kim; Sung Dae Kim; Sang Joon Park; Dongmi Kwak; Jun Hwan Oh; Chae Kyu Park; Man Hee Rhee

doi:10.1016/j.jgr.2017.04.004

Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL ^–/– mice

Evelyn Saba
, Seung Hyung Kim
, Sung Dae Kim
, Sang Joon Park
, Dongmi Kwak
, Jun Hwan Oh
, Chae Kyu Park
, Man Hee Rhee

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

In this study, we precisely showed how the Rg3-enriched red ginseng extract (Rg3-RGE) lowers glucose, triglyceride, and low-density lipoprotein (LDL) levels in LDL ^–/– mice. Aspartate aminotransferase/serum glutamic-oxaloacetic transaminase), alanine aminotransferase /serum glutamate-pyruvate transaminase, and steatohepatitis were found to be reduced, and atheroma formation was inhibited by Rg3-enriched red ginseng extract.

Original language	English
Pages (from-to)	352-355
Number of pages	4
Journal	Journal of Ginseng Research
Volume	42
Issue number	3
DOIs	https://doi.org/10.1016/j.jgr.2017.04.004
State	Published - Jul 2018

Keywords

Rg3-enriched Korean Red Ginseng extract
antiatheromatic
antidiabetic
antihypercholesterolemic

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jgr.2017.04.004

Cite this

Saba, E., Kim, S. H., Kim, S. D., Park, S. J., Kwak, D., Oh, J. H., Park, C. K., & Rhee, M. H. (2018). Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL ^–/– mice Journal of Ginseng Research, 42(3), 352-355. https://doi.org/10.1016/j.jgr.2017.04.004

@article{1ad3daf7ba9048aaa22d50d9cbb3e19e,

title = " Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL –/– mice ",

abstract = " In this study, we precisely showed how the Rg3-enriched red ginseng extract (Rg3-RGE) lowers glucose, triglyceride, and low-density lipoprotein (LDL) levels in LDL –/– mice. Aspartate aminotransferase/serum glutamic-oxaloacetic transaminase), alanine aminotransferase /serum glutamate-pyruvate transaminase, and steatohepatitis were found to be reduced, and atheroma formation was inhibited by Rg3-enriched red ginseng extract.",

keywords = "Rg3-enriched Korean Red Ginseng extract, antiatheromatic, antidiabetic, antihypercholesterolemic",

author = "Evelyn Saba and Kim, \{Seung Hyung\} and Kim, \{Sung Dae\} and Park, \{Sang Joon\} and Dongmi Kwak and Oh, \{Jun Hwan\} and Park, \{Chae Kyu\} and Rhee, \{Man Hee\}",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2018",

month = jul,

doi = "10.1016/j.jgr.2017.04.004",

language = "English",

volume = "42",

pages = "352--355",

journal = "Journal of Ginseng Research",

issn = "1226-8453",

publisher = "Elsevier B.V.",

number = "3",

}

Saba, E, Kim, SH, Kim, SD , Park, SJ , Kwak, D, Oh, JH, Park, CK & Rhee, MH 2018, ' Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL ^–/– mice ', Journal of Ginseng Research, vol. 42, no. 3, pp. 352-355. https://doi.org/10.1016/j.jgr.2017.04.004

Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL ^–/– mice . / Saba, Evelyn; Kim, Seung Hyung; Kim, Sung Dae et al.
In: Journal of Ginseng Research, Vol. 42, No. 3, 07.2018, p. 352-355.

Research output: Contribution to journal › Article › peer-review

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AU - Saba, Evelyn

AU - Kim, Seung Hyung

AU - Kim, Sung Dae

AU - Park, Sang Joon

AU - Kwak, Dongmi

AU - Oh, Jun Hwan

AU - Park, Chae Kyu

AU - Rhee, Man Hee

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N2 - In this study, we precisely showed how the Rg3-enriched red ginseng extract (Rg3-RGE) lowers glucose, triglyceride, and low-density lipoprotein (LDL) levels in LDL –/– mice. Aspartate aminotransferase/serum glutamic-oxaloacetic transaminase), alanine aminotransferase /serum glutamate-pyruvate transaminase, and steatohepatitis were found to be reduced, and atheroma formation was inhibited by Rg3-enriched red ginseng extract.

AB - In this study, we precisely showed how the Rg3-enriched red ginseng extract (Rg3-RGE) lowers glucose, triglyceride, and low-density lipoprotein (LDL) levels in LDL –/– mice. Aspartate aminotransferase/serum glutamic-oxaloacetic transaminase), alanine aminotransferase /serum glutamate-pyruvate transaminase, and steatohepatitis were found to be reduced, and atheroma formation was inhibited by Rg3-enriched red ginseng extract.

KW - Rg3-enriched Korean Red Ginseng extract

KW - antiatheromatic

KW - antidiabetic

KW - antihypercholesterolemic

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