Amino alcohol-derived chiral stationary phases

David Jin Han Seog; Nguyen van Kien; Jae Jeong Ryoo

doi:10.1002/chir.23574

Amino alcohol-derived chiral stationary phases

David Jin Han Seog, Nguyen van Kien, Jae Jeong Ryoo

Department of Chemical Science Education

Kyungpook National University

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

An updated minireview of chiral stationary phases (CSPs) based on amino alcohols is presented. In this minireview, we focused on amino alcohols as starting materials in preparation of chiral catalysts for asymmetric organic synthesis and CSPs for chiral separations. Among the various CSPs, we summarized the important developments and applications of the amino alcohol-based Pirkle-type CSPs, ligand exchange CSPs, α-amino acid-derived amino alcohol CSPs, and symmetric CSPs from their first appearance to the present day to propose ideas for the development of new CSPs with improved performance.

Original language	English
Pages (from-to)	739-752
Number of pages	14
Journal	Chirality
Volume	35
Issue number	10
DOIs	https://doi.org/10.1002/chir.23574
State	Published - Oct 2023

Keywords

amino alcohol
chiral separation
chiral stationary phases
HPLC
symmetric CSPs

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10.1002/chir.23574

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title = "Amino alcohol-derived chiral stationary phases",

abstract = "An updated minireview of chiral stationary phases (CSPs) based on amino alcohols is presented. In this minireview, we focused on amino alcohols as starting materials in preparation of chiral catalysts for asymmetric organic synthesis and CSPs for chiral separations. Among the various CSPs, we summarized the important developments and applications of the amino alcohol-based Pirkle-type CSPs, ligand exchange CSPs, α-amino acid-derived amino alcohol CSPs, and symmetric CSPs from their first appearance to the present day to propose ideas for the development of new CSPs with improved performance.",

keywords = "amino alcohol, chiral separation, chiral stationary phases, HPLC, symmetric CSPs",

author = "Seog, {David Jin Han} and {van Kien}, Nguyen and Ryoo, {Jae Jeong}",

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year = "2023",

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TY - JOUR

T1 - Amino alcohol-derived chiral stationary phases

AU - Seog, David Jin Han

AU - van Kien, Nguyen

AU - Ryoo, Jae Jeong

PY - 2023/10

Y1 - 2023/10

N2 - An updated minireview of chiral stationary phases (CSPs) based on amino alcohols is presented. In this minireview, we focused on amino alcohols as starting materials in preparation of chiral catalysts for asymmetric organic synthesis and CSPs for chiral separations. Among the various CSPs, we summarized the important developments and applications of the amino alcohol-based Pirkle-type CSPs, ligand exchange CSPs, α-amino acid-derived amino alcohol CSPs, and symmetric CSPs from their first appearance to the present day to propose ideas for the development of new CSPs with improved performance.

AB - An updated minireview of chiral stationary phases (CSPs) based on amino alcohols is presented. In this minireview, we focused on amino alcohols as starting materials in preparation of chiral catalysts for asymmetric organic synthesis and CSPs for chiral separations. Among the various CSPs, we summarized the important developments and applications of the amino alcohol-based Pirkle-type CSPs, ligand exchange CSPs, α-amino acid-derived amino alcohol CSPs, and symmetric CSPs from their first appearance to the present day to propose ideas for the development of new CSPs with improved performance.

KW - amino alcohol

KW - chiral separation

KW - chiral stationary phases

KW - HPLC

KW - symmetric CSPs

UR - http://www.scopus.com/inward/record.url?scp=85158084231&partnerID=8YFLogxK

U2 - 10.1002/chir.23574

DO - 10.1002/chir.23574

M3 - Review article

C2 - 37144722

AN - SCOPUS:85158084231

SN - 0899-0042

VL - 35

SP - 739

EP - 752

JO - Chirality

JF - Chirality

IS - 10

ER -

Amino alcohol-derived chiral stationary phases

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Keywords

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