Amoxicillin

Yong Hwan Kwon

doi:10.1007/978-981-287-706-2_37

Amoxicillin

Yong Hwan Kwon

Department of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

4 Scopus citations

Abstract

Treatment of Helicobacterpylori (H.pylori) is warranted and normally done with combination of antibiotics (such as amoxicillin, clarithromycin, or others) and a proton pump inhibitor. However, the eradication rate of legacy triple therapy has been decreasing because of the increase in resistance to clarithromycin. Likewise, treatment failure due to amoxicillin, a primary antimicrobial agent for H. pylori eradication, resistance has been noted since 20 years ago. Increasing levels of resistance to amoxicillin contribute to treatment failures, and higher levels of resistance are believed to be due to multiple genetic mutations. However, the exact mechanism of amoxicillin resistance and its contribution to eradication failure has not been fully elucidated.

Original language	English
Title of host publication	Helicobacter pylori
Publisher	Springer Singapore
Pages	387-396
Number of pages	10
ISBN (Electronic)	9789812877062
ISBN (Print)	9789812877055
DOIs	https://doi.org/10.1007/978-981-287-706-2_37
State	Published - 16 Jun 2016

Keywords

Amoxicillin
Antibiotic resistance
Eradication
Helicobacterpylori

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10.1007/978-981-287-706-2_37

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Amoxicillin

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