An anti-influenza component of the bark of alnus japonica

Nguyen Huu Tung; Hyuk Joon Kwon; Jae Hong Kim; Jeong Chan Ra; Jeong Ah Kim; Young Ho Kim

doi:10.1007/s12272-010-0303-5

An anti-influenza component of the bark of alnus japonica

Nguyen Huu Tung, Hyuk Joon Kwon, Jae Hong Kim, Jeong Chan Ra, Jeong Ah Kim, Young Ho Kim

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43 Scopus citations

Abstract

This study to identify anti-influenza components of the bark of Alnus japonica resulted in the isolation of four lupane-type triterpenes (1-4) and one steroid (5). Their structures were characterized on the basis of physicochemical properties, NMR evidence, and ESI-MS data compared with reported data in the literature. Betulinic aldehyde (3) exhibited a particularly strong anti-influenza effect against KBNP-0028 relative to a positive control.

Original language	English
Pages (from-to)	363-367
Number of pages	5
Journal	Archives of Pharmacal Research
Volume	33
Issue number	3
DOIs	https://doi.org/10.1007/s12272-010-0303-5
State	Published - Mar 2010

Keywords

Alnus japonica
Anti-influenza
Betulaceae
KBNP-0028
Lupane triterpene

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10.1007/s12272-010-0303-5

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title = "An anti-influenza component of the bark of alnus japonica",

abstract = "This study to identify anti-influenza components of the bark of Alnus japonica resulted in the isolation of four lupane-type triterpenes (1-4) and one steroid (5). Their structures were characterized on the basis of physicochemical properties, NMR evidence, and ESI-MS data compared with reported data in the literature. Betulinic aldehyde (3) exhibited a particularly strong anti-influenza effect against KBNP-0028 relative to a positive control.",

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author = "Tung, {Nguyen Huu} and Kwon, {Hyuk Joon} and Kim, {Jae Hong} and Ra, {Jeong Chan} and Kim, {Jeong Ah} and Kim, {Young Ho}",

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AU - Kwon, Hyuk Joon

AU - Kim, Jae Hong

AU - Ra, Jeong Chan

AU - Kim, Jeong Ah

AU - Kim, Young Ho

PY - 2010/3

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AB - This study to identify anti-influenza components of the bark of Alnus japonica resulted in the isolation of four lupane-type triterpenes (1-4) and one steroid (5). Their structures were characterized on the basis of physicochemical properties, NMR evidence, and ESI-MS data compared with reported data in the literature. Betulinic aldehyde (3) exhibited a particularly strong anti-influenza effect against KBNP-0028 relative to a positive control.

KW - Alnus japonica

KW - Anti-influenza

KW - Betulaceae

KW - KBNP-0028

KW - Lupane triterpene

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JO - Archives of Pharmacal Research

JF - Archives of Pharmacal Research

IS - 3

ER -

An anti-influenza component of the bark of alnus japonica

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