An anti-influenza component of the bark of alnus japonica

  • Nguyen Huu Tung
  • , Hyuk Joon Kwon
  • , Jae Hong Kim
  • , Jeong Chan Ra
  • , Jeong Ah Kim
  • , Young Ho Kim

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

This study to identify anti-influenza components of the bark of Alnus japonica resulted in the isolation of four lupane-type triterpenes (1-4) and one steroid (5). Their structures were characterized on the basis of physicochemical properties, NMR evidence, and ESI-MS data compared with reported data in the literature. Betulinic aldehyde (3) exhibited a particularly strong anti-influenza effect against KBNP-0028 relative to a positive control.

Original languageEnglish
Pages (from-to)363-367
Number of pages5
JournalArchives of Pharmacal Research
Volume33
Issue number3
DOIs
StatePublished - Mar 2010

Keywords

  • Alnus japonica
  • Anti-influenza
  • Betulaceae
  • KBNP-0028
  • Lupane triterpene

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