An approach for quinolines via palladium-catalyzed Heck coupling followed by cyclization

Chan Sik Cho, Jun Uk Kim

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

2-Iodoaniline reacts with α,β-unsaturated carbonyl compounds in DMF at 100 °C in the presence of a catalytic amount of a palladium catalyst along with a base to afford the corresponding quinolones or quinolines in moderate to good yields.

Original languageEnglish
Pages (from-to)3775-3778
Number of pages4
JournalTetrahedron Letters
Volume48
Issue number22
DOIs
StatePublished - 28 May 2007

Keywords

  • Alkenes
  • Cyclization
  • Heck reaction
  • Palladium catalyst
  • Quinolines
  • Quinolones

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