Abstract
We report the design and fabrication of an integrated Mach-Zehnder interferometric (MZI) biochip based on silicon oxynitride layers deposited with a plasma-enhanced chemical vapor deposition (PECVD) process. A rib waveguide for an integrated MZI sensor has been designed to have a high surface sensitivity and a single-mode behavior by using an effective index method. The integrated MZI chip operating at 637 nm is fabricated via conventional photolithography and reactive ion etching. As a biosensor application, the real-time and label-free detection of the covalent immobilization and hybridization of DNA strands is performed and verified with this device.
Original language | English |
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Pages (from-to) | 954-959 |
Number of pages | 6 |
Journal | Current Applied Physics |
Volume | 14 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2014 |
Keywords
- DNA
- Integrated Mach-Zehnder interferometric biochip
- Plasma-enhanced chemical vapor deposition
- Silicon oxynitride layers