An unusual palladium-catalyzed carbonylative cyclization of β-bromovinyl aldehydes leading to lactones

Chan Sik Cho, Hyung Sup Shim

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

β-Bromovinyl aldehydes are carbonylatively cyclized under carbon monoxide pressure in MeCN at 100 °C in the presence of a catalytic amount of a palladium catalyst along with a base to give the corresponding lactones in high yields.

Original languageEnglish
Pages (from-to)3835-3837
Number of pages3
JournalTetrahedron Letters
Volume47
Issue number23
DOIs
StatePublished - 5 Jun 2006

Keywords

  • β-Bromovinyl aldehydes
  • Carbon monoxide
  • Carbonylative cyclization
  • Lactones
  • Palladium catalyst

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