Anti-inflammatory lignans from the fruits of acanthopanax sessiliflorus

Dae Young Lee; Kyeong Hwa Seo; Rak Hun Jeong; Sang Min Lee; Geum Soog Kim; Hyung Jun Noh; Seung Yu Kim; Gye Won Kim; Ji Young Kim; Nam In Baek

doi:10.3390/molecules18010041

Anti-inflammatory lignans from the fruits of acanthopanax sessiliflorus

Dae Young Lee, Kyeong Hwa Seo, Rak Hun Jeong, Sang Min Lee, Geum Soog Kim, Hyung Jun Noh, Seung Yu Kim, Gye Won Kim, Ji Young Kim, Nam In Baek

School of Life Science and Biotechnology

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

A new lignan, named acanthosessilin A (1), as well as eight known lignan and lignan glycosides 2-9 were isolated from an ethanolic extract of Acanthopanax sessiliflorus fruits. The chemical structures were determined by spectroscopic methods, including HR-EIMS, 1D NMR (¹H, ¹³C, DEPT), 2D NMR (gCOSY, gHSQC, gHMBC, NOESY), and IR spectroscopy. All isolated compounds were tested for the ability to inhibit LPS-induced nitric oxide production in RAW264.7 macrophages.

Original language	English
Pages (from-to)	41-49
Number of pages	9
Journal	Molecules
Volume	18
Issue number	1
DOIs	https://doi.org/10.3390/molecules18010041
State	Published - Jan 2013

Keywords

Acanthopanax sessiliflorus
Acanthosessilin A
Lignan
Nitric oxide

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10.3390/molecules18010041

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abstract = "A new lignan, named acanthosessilin A (1), as well as eight known lignan and lignan glycosides 2-9 were isolated from an ethanolic extract of Acanthopanax sessiliflorus fruits. The chemical structures were determined by spectroscopic methods, including HR-EIMS, 1D NMR (1H, 13C, DEPT), 2D NMR (gCOSY, gHSQC, gHMBC, NOESY), and IR spectroscopy. All isolated compounds were tested for the ability to inhibit LPS-induced nitric oxide production in RAW264.7 macrophages.",

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AU - Noh, Hyung Jun

AU - Kim, Seung Yu

AU - Kim, Gye Won

AU - Kim, Ji Young

AU - Baek, Nam In

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Anti-inflammatory lignans from the fruits of acanthopanax sessiliflorus

Abstract

Keywords

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