Antibacterial Substance Produced by Streptococcus faecium under Anaerobic Culture

Seung Chun Park; Chang Jin Kim; Ki Hong Yoon; Tae Kwang Oh; Masakazu Uramoto; Hyo in Yun

doi:10.1271/bbb.59.1966

Antibacterial Substance Produced by Streptococcus faecium under Anaerobic Culture

Seung Chun Park, Chang Jin Kim, Ki Hong Yoon, Tae Kwang Oh, Masakazu Uramoto, Hyo in Yun

Department of Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A facultative anaerobe isolated from Korean domestic soil produced an antibacterial substance under strict anaerobic conditions. Based on the morphological and biochemical tests, and cellular fatty acid profiles, the anaerobe was identified as Streptococcus faecium. An antimicrobial compound produced from the S. faecium was identified as 3,7,12-trihydroxy-24-cholanic acid methylester on the basis of its physico-chemical analysis. This substance had potent antibacterial activities against a test organism harboring multiple antibiotic resistance markers, and a variety of pathogenic bacteria. The isolated S. faecium produced lactic acid as well as the antibiotic compound under the anaerobic conditions.

Original language	English
Pages (from-to)	1966-1967
Number of pages	2
Journal	Bioscience, Biotechnology and Biochemistry
Volume	59
Issue number	10
DOIs	https://doi.org/10.1271/bbb.59.1966
State	Published - 1995

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abstract = "A facultative anaerobe isolated from Korean domestic soil produced an antibacterial substance under strict anaerobic conditions. Based on the morphological and biochemical tests, and cellular fatty acid profiles, the anaerobe was identified as Streptococcus faecium. An antimicrobial compound produced from the S. faecium was identified as 3,7,12-trihydroxy-24-cholanic acid methylester on the basis of its physico-chemical analysis. This substance had potent antibacterial activities against a test organism harboring multiple antibiotic resistance markers, and a variety of pathogenic bacteria. The isolated S. faecium produced lactic acid as well as the antibiotic compound under the anaerobic conditions.",

author = "Park, {Seung Chun} and Kim, {Chang Jin} and Yoon, {Ki Hong} and Oh, {Tae Kwang} and Masakazu Uramoto and Yun, {Hyo in}",

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doi = "10.1271/bbb.59.1966",

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AU - Park, Seung Chun

AU - Kim, Chang Jin

AU - Yoon, Ki Hong

AU - Oh, Tae Kwang

AU - Uramoto, Masakazu

AU - Yun, Hyo in

PY - 1995

Y1 - 1995

N2 - A facultative anaerobe isolated from Korean domestic soil produced an antibacterial substance under strict anaerobic conditions. Based on the morphological and biochemical tests, and cellular fatty acid profiles, the anaerobe was identified as Streptococcus faecium. An antimicrobial compound produced from the S. faecium was identified as 3,7,12-trihydroxy-24-cholanic acid methylester on the basis of its physico-chemical analysis. This substance had potent antibacterial activities against a test organism harboring multiple antibiotic resistance markers, and a variety of pathogenic bacteria. The isolated S. faecium produced lactic acid as well as the antibiotic compound under the anaerobic conditions.

AB - A facultative anaerobe isolated from Korean domestic soil produced an antibacterial substance under strict anaerobic conditions. Based on the morphological and biochemical tests, and cellular fatty acid profiles, the anaerobe was identified as Streptococcus faecium. An antimicrobial compound produced from the S. faecium was identified as 3,7,12-trihydroxy-24-cholanic acid methylester on the basis of its physico-chemical analysis. This substance had potent antibacterial activities against a test organism harboring multiple antibiotic resistance markers, and a variety of pathogenic bacteria. The isolated S. faecium produced lactic acid as well as the antibiotic compound under the anaerobic conditions.

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VL - 59

SP - 1966

EP - 1967

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

IS - 10

ER -

Antibacterial Substance Produced by Streptococcus faecium under Anaerobic Culture

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