Antifungal activities of β-thujaplicin originated in Chamaecyparis obtusa

Yubin Kwon, Hyun Sang Kim, Hyun Woo Kim, Dong Woon Lee, Yong Hwa Choi

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Environment-friendly, commercially-available agricultural products were investigated for antimicrobial activity against Sclerotinia sclerotiorum, as a pathogen of sclerotium disease. Then β-thujaplicin from Chamaecyparis obtuse was investigated for antifungal activity against six kinds of pathogenic fungi. It showed a statistically significant (p <0.001) growth inhibition effect on Sclerotinia sclerotiorum as a pathogen of sclerotium disease, Rhizoctonia solani AG-4 as a pathogen of damping off, Phytophthora capsici as a pathogen of phytophthora blight, and Colletotrichum coccodes as a pathogen of anthracnose at a concentration of 50 ppm and on Stemphylium solani as a pathogen of spotting disease and Alternaria alternata as a pathogen of black mold at a concentration of 100 ppm. In conclusion, these results indicate that it may be possible to develop environment-friendly agricultural products using β-thujaplicin compounds.

Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalJournal of Applied Biological Chemistry
Volume60
Issue number3
DOIs
StatePublished - Sep 2017

Keywords

  • Antifungal active substance
  • Chamaecyparis obtusa
  • Hinokitiol
  • Sclerotinia sclerotiorum
  • β-thujaplicin

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