Antifungal potential of essential oil and ethanol extracts of Lonicera japonica thunb. against dermatophytes

Atiqur Rahman; Sharif M. Al-Reza; Shah Alam Siddiqui; Taehyun Chang; Sun Chul Kang

Antifungal potential of essential oil and ethanol extracts of Lonicera japonica thunb. against dermatophytes

Atiqur Rahman, Sharif M. Al-Reza, Shah Alam Siddiqui, Taehyun Chang, Sun Chul Kang

Department of Crop Science

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

The antifungal potential of essential oil and ethanolic leaf extracts of Lonicera japonica Thunb. was evaluated for controlling the growth of dermatophytes. The oil (1,000 ppm) and extracts (1,500 ppm) of L. japonica revealed 55.1-70.3% and 40.1-65.5% antidermatophytic effect against Microsporum canis KCTC 6348, 6349, 6591, Trichophyton rubrum KCTC 6345, 6352, 6375, Trichophyton mentagrophytes KCTC 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations ranging from 62.5-500 and 125-1,000 μg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytes as well as concentration and time-dependent kinetic inhibition of M. canis KCTC 6348. The results demonstrated that L. japonica oil and extracts could be potential sources of natural fungicides to protect human and animals from fungal infections.

Original language	English
Pages (from-to)	427-436
Number of pages	10
Journal	EXCLI Journal
Volume	13
State	Published - 28 Apr 2014

Keywords

Antidermatophytic activity
Essential oil
Ethanolic extracts
Lonicera japonica thunb.
Skin infectious fungal pathogens

Cite this

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title = "Antifungal potential of essential oil and ethanol extracts of Lonicera japonica thunb. against dermatophytes",

abstract = "The antifungal potential of essential oil and ethanolic leaf extracts of Lonicera japonica Thunb. was evaluated for controlling the growth of dermatophytes. The oil (1,000 ppm) and extracts (1,500 ppm) of L. japonica revealed 55.1-70.3% and 40.1-65.5% antidermatophytic effect against Microsporum canis KCTC 6348, 6349, 6591, Trichophyton rubrum KCTC 6345, 6352, 6375, Trichophyton mentagrophytes KCTC 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations ranging from 62.5-500 and 125-1,000 μg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytes as well as concentration and time-dependent kinetic inhibition of M. canis KCTC 6348. The results demonstrated that L. japonica oil and extracts could be potential sources of natural fungicides to protect human and animals from fungal infections.",

keywords = "Antidermatophytic activity, Essential oil, Ethanolic extracts, Lonicera japonica thunb., Skin infectious fungal pathogens",

author = "Atiqur Rahman and Al-Reza, {Sharif M.} and Siddiqui, {Shah Alam} and Taehyun Chang and Kang, {Sun Chul}",

year = "2014",

month = apr,

day = "28",

language = "English",

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pages = "427--436",

journal = "EXCLI Journal",

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T1 - Antifungal potential of essential oil and ethanol extracts of Lonicera japonica thunb. against dermatophytes

AU - Rahman, Atiqur

AU - Al-Reza, Sharif M.

AU - Siddiqui, Shah Alam

AU - Chang, Taehyun

AU - Kang, Sun Chul

PY - 2014/4/28

Y1 - 2014/4/28

N2 - The antifungal potential of essential oil and ethanolic leaf extracts of Lonicera japonica Thunb. was evaluated for controlling the growth of dermatophytes. The oil (1,000 ppm) and extracts (1,500 ppm) of L. japonica revealed 55.1-70.3% and 40.1-65.5% antidermatophytic effect against Microsporum canis KCTC 6348, 6349, 6591, Trichophyton rubrum KCTC 6345, 6352, 6375, Trichophyton mentagrophytes KCTC 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations ranging from 62.5-500 and 125-1,000 μg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytes as well as concentration and time-dependent kinetic inhibition of M. canis KCTC 6348. The results demonstrated that L. japonica oil and extracts could be potential sources of natural fungicides to protect human and animals from fungal infections.

AB - The antifungal potential of essential oil and ethanolic leaf extracts of Lonicera japonica Thunb. was evaluated for controlling the growth of dermatophytes. The oil (1,000 ppm) and extracts (1,500 ppm) of L. japonica revealed 55.1-70.3% and 40.1-65.5% antidermatophytic effect against Microsporum canis KCTC 6348, 6349, 6591, Trichophyton rubrum KCTC 6345, 6352, 6375, Trichophyton mentagrophytes KCTC 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations ranging from 62.5-500 and 125-1,000 μg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytes as well as concentration and time-dependent kinetic inhibition of M. canis KCTC 6348. The results demonstrated that L. japonica oil and extracts could be potential sources of natural fungicides to protect human and animals from fungal infections.

KW - Antidermatophytic activity

KW - Essential oil

KW - Ethanolic extracts

KW - Lonicera japonica thunb.

KW - Skin infectious fungal pathogens

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M3 - Article

AN - SCOPUS:84899651039

SN - 1611-2156

VL - 13

SP - 427

EP - 436

JO - EXCLI Journal

JF - EXCLI Journal

ER -

Antifungal potential of essential oil and ethanol extracts of Lonicera japonica thunb. against dermatophytes

Abstract

Keywords

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