Application of scaffolds for artificial skin in regenerative medicine

Tissue engineering and regenerative medicine is a rapidly growing and emerging as an interdisciplinary field in the area of biological and medical cooperation, which aims to regenerate new biological material for replacing diseased or damaged tissues or organs. Tissue engineering for skin, as the largest organ of the human body, has been developed from early periods. Nowadays, skin is readily accessible for direct tissue modulation, for example, gene therapy or stem cell therapy. And many researchers are approaching to replace scar or nonfunctional tissue using biological scaffolds for skin regeneration, such as collagen, gelatin, fibrin glue, chitosan, poly(lactic acid) (PLA), poly(lactic-co-glycolic acid) (PLGA), and so on. Furthermore, many tissue-engineered products are showing, such as Epicel^®, Integra^®, Alloderm^®, Transcyte^®, Apligraf^®, and so on. And their clinical applications are reported.