Assessment of fluid and nutritional status using multifrequency bioelectrical impedance analysis in peritoneal dialysis patients

Background/Aims: The purpose of this study was to evaluate the clinical usefulness and relevance of bioelectrical impedance analysis (BIA) for assessing the fluid and nutritional status in peritoneal dialysis (PD) patients. Methods: Statistical analyses between various measures of fluid and nutritional status were performed in 106 cases of 64 patients. Results: Extracellular fluid/total body water (ECF/TBW) was correlated with systolic blood pressure, extremity edema, and antihypertensive medications (p = 0.042, p < 0.001, and p = 0.029, respectively). Body cell mass (BCM)/height² was correlated with SGA rating and PCR (p < 0.001 and p = 0.002, respectively). ECF/TBW and BCM/height² significantly predicted extremity edema (p < 0.001) and SGA rating (p = 0.001), respectively. ROC analysis yielded an ECF/TBW cut-off of 0.36 and a BCM/height² cut-off of 11.23. When the BCM/height² cut-off of 11.23 was applied to subclinical patients (SGA score ≥6), a significant difference in SGA rating was detected in subgroups (p = 0.010). Conclusion: BIA yields useful and relevant information about hydration and nutritional status in PD patients.