Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen

Honglin Jia; M. Alaa Terkawi; Gabriel Oluga Aboge; Youn Kyoung Goo; Jinlin Zhou; Eung Goo Lee; Yoshifumi Nishikawa; Ikuo Igarashi; Kozo Fujisaki; Xuenan Xuan

doi:10.1016/j.exppara.2007.07.005

Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen

Honglin Jia, M. Alaa Terkawi, Gabriel Oluga Aboge, Youn Kyoung Goo, Jinlin Zhou, Eung Goo Lee, Yoshifumi Nishikawa, Ikuo Igarashi, Kozo Fujisaki, Xuenan Xuan

Department of Medicine

Obihiro University of Agriculture and Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.

Original language	English
Pages (from-to)	146-149
Number of pages	4
Journal	Experimental Parasitology
Volume	118
Issue number	1
DOIs	https://doi.org/10.1016/j.exppara.2007.07.005
State	Published - Jan 2008

Keywords

Babesia gibsoni
BgIRA
ELISA

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.exppara.2007.07.005

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title = "Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen",

abstract = "In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.",

keywords = "Babesia gibsoni, BgIRA, ELISA",

author = "Honglin Jia and Terkawi, {M. Alaa} and Aboge, {Gabriel Oluga} and Goo, {Youn Kyoung} and Jinlin Zhou and Lee, {Eung Goo} and Yoshifumi Nishikawa and Ikuo Igarashi and Kozo Fujisaki and Xuenan Xuan",

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T2 - Identification of an immunodominant, interspersed repeat antigen

AU - Jia, Honglin

AU - Terkawi, M. Alaa

AU - Aboge, Gabriel Oluga

AU - Goo, Youn Kyoung

AU - Zhou, Jinlin

AU - Lee, Eung Goo

AU - Nishikawa, Yoshifumi

AU - Igarashi, Ikuo

AU - Fujisaki, Kozo

AU - Xuan, Xuenan

PY - 2008/1

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AB - In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.

KW - Babesia gibsoni

KW - BgIRA

KW - ELISA

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JO - Experimental Parasitology

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Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen

Abstract

Keywords

UN SDGs

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