Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen

Honglin Jia; M. Alaa Terkawi; Gabriel Oluga Aboge; Youn Kyoung Goo; Jinlin Zhou; Eung Goo Lee; Yoshifumi Nishikawa; Ikuo Igarashi; Kozo Fujisaki; Xuenan Xuan

doi:10.1016/j.exppara.2007.07.005

Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen

Honglin Jia
, M. Alaa Terkawi
, Gabriel Oluga Aboge
, Youn Kyoung Goo
, Jinlin Zhou
, Eung Goo Lee
, Yoshifumi Nishikawa
, Ikuo Igarashi
, Kozo Fujisaki
, Xuenan Xuan

Department of Medicine

Obihiro University of Agriculture and Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.

Original language	English
Pages (from-to)	146-149
Number of pages	4
Journal	Experimental Parasitology
Volume	118
Issue number	1
DOIs	https://doi.org/10.1016/j.exppara.2007.07.005
State	Published - Jan 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Babesia gibsoni
BgIRA
ELISA

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10.1016/j.exppara.2007.07.005

Cite this

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title = "Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen",

abstract = "In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.",

keywords = "Babesia gibsoni, BgIRA, ELISA",

author = "Honglin Jia and Terkawi, \{M. Alaa\} and Aboge, \{Gabriel Oluga\} and Goo, \{Youn Kyoung\} and Jinlin Zhou and Lee, \{Eung Goo\} and Yoshifumi Nishikawa and Ikuo Igarashi and Kozo Fujisaki and Xuenan Xuan",

year = "2008",

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doi = "10.1016/j.exppara.2007.07.005",

language = "English",

volume = "118",

pages = "146--149",

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T1 - Babesia gibsoni

T2 - Identification of an immunodominant, interspersed repeat antigen

AU - Jia, Honglin

AU - Terkawi, M. Alaa

AU - Aboge, Gabriel Oluga

AU - Goo, Youn Kyoung

AU - Zhou, Jinlin

AU - Lee, Eung Goo

AU - Nishikawa, Yoshifumi

AU - Igarashi, Ikuo

AU - Fujisaki, Kozo

AU - Xuan, Xuenan

PY - 2008/1

Y1 - 2008/1

N2 - In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.

AB - In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.

KW - Babesia gibsoni

KW - BgIRA

KW - ELISA

UR - https://www.scopus.com/pages/publications/37349080906

U2 - 10.1016/j.exppara.2007.07.005

DO - 10.1016/j.exppara.2007.07.005

M3 - Article

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AN - SCOPUS:37349080906

SN - 0014-4894

VL - 118

SP - 146

EP - 149

JO - Experimental Parasitology

JF - Experimental Parasitology

IS - 1

ER -

Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen

Abstract

UN SDGs

Keywords

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