Bio-inspired autonomous sentinel system for screening invasive pathogens

S. Li, H. C. Wikle, Y. Chai, M. K. Park, S. Horikawa, B. A. Chin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This paper presents the results of a preliminary investigation to develop a bio-inspired autonomous pathogen screening system that mimics the function of natural immune systems, such as white blood cells. This screening system is comprised of multiple magnetoelastic (ME) biosentinels. The sentinels are composed of a wireless magnetoelastic resonator immobilized with a bio-probe layer that captures specific target pathogens. The biosentinels are actuated, monitored, and controlled wirelessly by external magnetic fields. The autonomous sentinel system is envisioned to have the capability of seeking out invasive pathogens in liquid environments, detecting and capturing them. In the paper, the proof-in-principal of the concept of autonomous sentinels is demonstrated by comparing the response of the sentinels in dynamic and static Salmonella analytes.

Original languageEnglish
Title of host publicationChemical Sensors 10 -and- MEMS/NEMS 10
PublisherElectrochemical Society Inc.
Pages53-59
Number of pages7
Edition12
ISBN (Print)9781607683605
DOIs
StatePublished - 2013
EventSymposia on Chemical Sensors 10 - Chemical and Biological Sensors and Analytical Systems and Microfabricated and Nanofabricated Systems for MEMS/NEMS 10 - 222nd ECS Meeting/PRiME 2012 - Honolulu, HI, United States
Duration: 7 Oct 201212 Oct 2012

Publication series

NameECS Transactions
Number12
Volume50
ISSN (Print)1938-5862
ISSN (Electronic)1938-6737

Conference

ConferenceSymposia on Chemical Sensors 10 - Chemical and Biological Sensors and Analytical Systems and Microfabricated and Nanofabricated Systems for MEMS/NEMS 10 - 222nd ECS Meeting/PRiME 2012
Country/TerritoryUnited States
CityHonolulu, HI
Period7/10/1212/10/12

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