Biological activity of ethanol extracts from Amelanchier asiatica fruits

Amelanchier asiatica fruits have been used as a traditional medical food. This research was investigated to assess angiotensin converting enzyme, xanthine oxidase (XOase) and elastase inhibitory activity and antioxidant activities. The content of total phenolic compounds in A. asiatica fruits extracts was 17.6mg/mL. In extracts, the electron donating ability by 1,1-diphenyl-2-picrylhydrazyl free radical scavenging test of A. asiatica fruits extracts was 90.18% at 200 μg/mL. The 2,2′- azinobis(3-ethylbenzothiazoline-6-sulfonic acid radical decolorization of A. asiatica fruits extracts was 98.81% at 200 μg/mL. The inhibition rate of the antioxidant protection factor was 1.03, and thiobarbituric acid reactive substance was 73.27% at 200 μg/mL. The XOase inhibition activity of A. asiatica fruits extracts of showed to be 13.19% at 200 μg/mL. The angiotensin converting enzyme activity was significantly inhibited by A. asiatica fruits extracts as 82.52% inhibitory rate at 200 μg/ mL. Elastase inhibitory activity in the A. asiatica fruits extracts (41.48% at 200 μg/mL) was higher than vitamin C (12.8% at 200 μg/mL). These results suggests that A. asiatica fruits extracts have the greatest property as a functional food and functional cosmetic source.