Cancer cell imaging by stable wet near-field scanning optical microscope with resonance tracking method

Kyoung Duck Park, Doo Jae Park, Mun Seok Jeong, Geun Chang Choi, Seung Gol Lee, Clare Chisu Byeon, Soo Bong Choi

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

We report on a successful topographical and optical imaging of various cancer cells in liquid and in air by using a stable wet near-field scanning optical microscope that utilizes a resonance tracking method. We observed a clear dehydration which gives rise to a decrease in the cell volume down to 51%. In addition, a micro-ball lens effect due to the round-shaped young cancer cells was observed from near-field imaging, where the refractive index of young cancer cells was deduced.

Original languageEnglish
Pages (from-to)1500-1503
Number of pages4
JournalJournal of the Korean Physical Society
Volume64
Issue number10
DOIs
StatePublished - May 2014

Keywords

  • Bio imaging
  • Nano imaging
  • NSOM
  • Optical property
  • Topography

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