TY - JOUR
T1 - Carbon nanomaterials and metallic nanoparticles-incorporated electrochemical sensors for small metabolites
T2 - Detection methodologies and applications
AU - Si, Yunpei
AU - Lee, Hye Jin
N1 - Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2020/8
Y1 - 2020/8
N2 - Detection of small metabolite biomarkers at different concentrations could be powerfully used for disease diagnosis and progression. To enhance detection capabilities, nanomaterials possessing excellent optical and electrochemical properties have been integrated into a wide range of sensing or detection platforms. This review will highlight recent developments in creating electrochemical sensors alongside biosensors using carbon nanomaterials and metallic nanoparticles that target small metabolites. Moreover, electrochemical sensors having different detection strategies toward metabolites (such as amino acids, amino acid–derived neurotransmitters, vitamins, adenosine triphosphate, and purine derivatives) will be discussed. Finally, certain challenging issues and future aspects of nanomaterials-integrated electrochemical sensors for small metabolites will be discussed.
AB - Detection of small metabolite biomarkers at different concentrations could be powerfully used for disease diagnosis and progression. To enhance detection capabilities, nanomaterials possessing excellent optical and electrochemical properties have been integrated into a wide range of sensing or detection platforms. This review will highlight recent developments in creating electrochemical sensors alongside biosensors using carbon nanomaterials and metallic nanoparticles that target small metabolites. Moreover, electrochemical sensors having different detection strategies toward metabolites (such as amino acids, amino acid–derived neurotransmitters, vitamins, adenosine triphosphate, and purine derivatives) will be discussed. Finally, certain challenging issues and future aspects of nanomaterials-integrated electrochemical sensors for small metabolites will be discussed.
KW - Aptasensor
KW - Electrochemical sensor
KW - Enzyme
KW - Molecularly imprinted polymer
KW - Nanomaterial
KW - Small metabolites
UR - http://www.scopus.com/inward/record.url?scp=85091563716&partnerID=8YFLogxK
U2 - 10.1016/j.coelec.2020.08.007
DO - 10.1016/j.coelec.2020.08.007
M3 - Review article
AN - SCOPUS:85091563716
SN - 2451-9103
VL - 22
SP - 234
EP - 243
JO - Current Opinion in Electrochemistry
JF - Current Opinion in Electrochemistry
ER -