Abstract
A spontaneous mutant was established in the ICR mouse strain. The affected mice became hyperactive at about 7 days of age, and then showed circling behavior. The body weight decreased significantly 2 weeks after birth, and developmental defects were revealed in the middle ear, cochlea, cochlear nerve, and semicircular canal areas. The mutation was inherited by an autosomal single recessive gene and is referred to as cir.
Original language | English |
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Pages (from-to) | 167-171 |
Number of pages | 5 |
Journal | Experimental Animals |
Volume | 51 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2002 |
Keywords
- Circling mouse
- Inner ear
- Organ of Corti