CNS relapsed T-cell lymphoma in a young cat

Kyoung Won Seo; Ye In Oh; Sei Myoung Han; Du Min Go; Jeong Ha Lee; Hwa Young Youn

doi:10.17555/ksvc.2014.06.31.3.226

CNS relapsed T-cell lymphoma in a young cat

Kyoung Won Seo, Ye In Oh, Sei Myoung Han, Du Min Go, Jeong Ha Lee, Hwa Young Youn

Department of Veterinary Medicine

Chungnam National University

Research output: Contribution to journal › Article › peer-review

Abstract

An 8-month-old domestic shorthair cat presented with decreased activity and anorexia. Diagnostic imaging revealed cranial mediastinal mass and enlarged mesenteric lymph nodes. Fine needle aspirates showed a marked increase in malignant lymphocytes. Multicentric lymphoma (stage V-b) was diagnosed. The cat treated with COP protocol chemotherapy, and complete remission was induced. CNS relapse developed 314 days after the initiation of chemotherapy. Treatment with rescue protocol greatly reduced the clinical signs for a short period. The cat was in partial remission for 33 days and overall survival time was 383 days. Multicentric T-cell lymphoma with brain involvement was confirmed after necropsy by histopathology and immunohistochemistry.

Original language	English
Pages (from-to)	226-232
Number of pages	7
Journal	Journal of Veterinary Clinics
Volume	31
Issue number	3
DOIs	https://doi.org/10.17555/ksvc.2014.06.31.3.226
State	Published - 2014

Keywords

Cat
Central nervous system
Cytarabine (cytosine arabinoside)
Relapsed lymphoma

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10.17555/ksvc.2014.06.31.3.226

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abstract = "An 8-month-old domestic shorthair cat presented with decreased activity and anorexia. Diagnostic imaging revealed cranial mediastinal mass and enlarged mesenteric lymph nodes. Fine needle aspirates showed a marked increase in malignant lymphocytes. Multicentric lymphoma (stage V-b) was diagnosed. The cat treated with COP protocol chemotherapy, and complete remission was induced. CNS relapse developed 314 days after the initiation of chemotherapy. Treatment with rescue protocol greatly reduced the clinical signs for a short period. The cat was in partial remission for 33 days and overall survival time was 383 days. Multicentric T-cell lymphoma with brain involvement was confirmed after necropsy by histopathology and immunohistochemistry.",

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AU - Seo, Kyoung Won

AU - Oh, Ye In

AU - Han, Sei Myoung

AU - Go, Du Min

AU - Lee, Jeong Ha

AU - Youn, Hwa Young

PY - 2014

Y1 - 2014

N2 - An 8-month-old domestic shorthair cat presented with decreased activity and anorexia. Diagnostic imaging revealed cranial mediastinal mass and enlarged mesenteric lymph nodes. Fine needle aspirates showed a marked increase in malignant lymphocytes. Multicentric lymphoma (stage V-b) was diagnosed. The cat treated with COP protocol chemotherapy, and complete remission was induced. CNS relapse developed 314 days after the initiation of chemotherapy. Treatment with rescue protocol greatly reduced the clinical signs for a short period. The cat was in partial remission for 33 days and overall survival time was 383 days. Multicentric T-cell lymphoma with brain involvement was confirmed after necropsy by histopathology and immunohistochemistry.

AB - An 8-month-old domestic shorthair cat presented with decreased activity and anorexia. Diagnostic imaging revealed cranial mediastinal mass and enlarged mesenteric lymph nodes. Fine needle aspirates showed a marked increase in malignant lymphocytes. Multicentric lymphoma (stage V-b) was diagnosed. The cat treated with COP protocol chemotherapy, and complete remission was induced. CNS relapse developed 314 days after the initiation of chemotherapy. Treatment with rescue protocol greatly reduced the clinical signs for a short period. The cat was in partial remission for 33 days and overall survival time was 383 days. Multicentric T-cell lymphoma with brain involvement was confirmed after necropsy by histopathology and immunohistochemistry.

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KW - Central nervous system

KW - Cytarabine (cytosine arabinoside)

KW - Relapsed lymphoma

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CNS relapsed T-cell lymphoma in a young cat

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