Comparison of monomeric and polymeric chiral stationary phases

Kwang Pill Lee; Seong Ho Choi; Soo Yeon Kim; Tae Hyuk Kim; Jae Jeong Ryoo; Kazutoku Ohta; Ji Ye Jin; Toyohide Takeuchi; Chuzo Fujimoto

doi:10.1016/S0021-9673(02)01462-0

Comparison of monomeric and polymeric chiral stationary phases

Kwang Pill Lee, Seong Ho Choi, Soo Yeon Kim, Tae Hyuk Kim, Jae Jeong Ryoo, Kazutoku Ohta, Ji Ye Jin, Toyohide Takeuchi, Chuzo Fujimoto

Department of Chemical Science Education

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Two-type polymeric chiral stationary phases (pCSPs) were prepared by surface grafting of chiral acryl-type monomers on a silica gel surface modified with 3-(trimethoxysilyl)propylmethacrylate. The prepared pCSPs were characterized by IR, FT-Raman, scanning electron microscopy, and elemental analysis. In addition, two-type monomeric chiral stationary phases (mCSPs) were also prepared. The racemic analytes were separated using the prepared mCSPs and pCSPs. The separation factor (α) and capacity factor (k₁) of the racemic analytes for the pCSP and mCSP were compared. The α and k₁ values of the mCSP were higher than those of the pCSP.

Original language	English
Pages (from-to)	111-118
Number of pages	8
Journal	Journal of Chromatography A
Volume	987
Issue number	1-2
DOIs	https://doi.org/10.1016/S0021-9673(02)01462-0
State	Published - 14 Feb 2003

Keywords

Amino acids
Chiral stationary phases, LC
Naphthylene methylethyl propanamide
Retention factor
Separation factor
Surface grafting

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10.1016/S0021-9673(02)01462-0

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title = "Comparison of monomeric and polymeric chiral stationary phases",

abstract = "Two-type polymeric chiral stationary phases (pCSPs) were prepared by surface grafting of chiral acryl-type monomers on a silica gel surface modified with 3-(trimethoxysilyl)propylmethacrylate. The prepared pCSPs were characterized by IR, FT-Raman, scanning electron microscopy, and elemental analysis. In addition, two-type monomeric chiral stationary phases (mCSPs) were also prepared. The racemic analytes were separated using the prepared mCSPs and pCSPs. The separation factor (α) and capacity factor (k1) of the racemic analytes for the pCSP and mCSP were compared. The α and k1 values of the mCSP were higher than those of the pCSP.",

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doi = "10.1016/S0021-9673(02)01462-0",

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TY - JOUR

T1 - Comparison of monomeric and polymeric chiral stationary phases

AU - Lee, Kwang Pill

AU - Choi, Seong Ho

AU - Kim, Soo Yeon

AU - Kim, Tae Hyuk

AU - Ryoo, Jae Jeong

AU - Ohta, Kazutoku

AU - Jin, Ji Ye

AU - Takeuchi, Toyohide

AU - Fujimoto, Chuzo

PY - 2003/2/14

Y1 - 2003/2/14

N2 - Two-type polymeric chiral stationary phases (pCSPs) were prepared by surface grafting of chiral acryl-type monomers on a silica gel surface modified with 3-(trimethoxysilyl)propylmethacrylate. The prepared pCSPs were characterized by IR, FT-Raman, scanning electron microscopy, and elemental analysis. In addition, two-type monomeric chiral stationary phases (mCSPs) were also prepared. The racemic analytes were separated using the prepared mCSPs and pCSPs. The separation factor (α) and capacity factor (k1) of the racemic analytes for the pCSP and mCSP were compared. The α and k1 values of the mCSP were higher than those of the pCSP.

AB - Two-type polymeric chiral stationary phases (pCSPs) were prepared by surface grafting of chiral acryl-type monomers on a silica gel surface modified with 3-(trimethoxysilyl)propylmethacrylate. The prepared pCSPs were characterized by IR, FT-Raman, scanning electron microscopy, and elemental analysis. In addition, two-type monomeric chiral stationary phases (mCSPs) were also prepared. The racemic analytes were separated using the prepared mCSPs and pCSPs. The separation factor (α) and capacity factor (k1) of the racemic analytes for the pCSP and mCSP were compared. The α and k1 values of the mCSP were higher than those of the pCSP.

KW - Amino acids

KW - Chiral stationary phases, LC

KW - Naphthylene methylethyl propanamide

KW - Retention factor

KW - Separation factor

KW - Surface grafting

UR - http://www.scopus.com/inward/record.url?scp=0037435967&partnerID=8YFLogxK

U2 - 10.1016/S0021-9673(02)01462-0

DO - 10.1016/S0021-9673(02)01462-0

M3 - Article

C2 - 12613803

AN - SCOPUS:0037435967

SN - 0021-9673

VL - 987

SP - 111

EP - 118

JO - Journal of Chromatography A

JF - Journal of Chromatography A

IS - 1-2

ER -

Comparison of monomeric and polymeric chiral stationary phases

Abstract

Keywords

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