Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia

Korean Network for Study on Infectious Diseases (KONSID)

doi:10.1016/j.diagmicrobio.2015.10.015

Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia

Korean Network for Study on Infectious Diseases (KONSID)

Department of Medicine

Asia Pacific Foundation for Infectious Diseases (APFID)
Sungkyunkwan University
Kyung Hee University
Seoul Veterans Hospital
Hallym University
Chungnam National University
Dankook University
Chonnam National University
Kyungpook National University
Keimyung University
Daegu Fatima Hospital
Changwon Fatima Hospital

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

We evaluated the molecular epidemiology and microbiological characteristics of extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) isolates that cause bacteremia in Korean hospitals, focusing especially on ST131. Our data suggest that ST131 isolates possessed more virulence traits and showed more multidrug resistance patterns than non-ST131 isolates. Among CTX-M-15 producers, the frequency of serum resistance was significantly higher in ST131 than in non-ST131. As in other parts of the world, the ESBL-EC ST131 clone has emerged and disseminated in both community and hospital settings in Korea, including in blood isolates in patients with bacteremia.

Original language	English
Pages (from-to)	102-104
Number of pages	3
Journal	Diagnostic Microbiology and Infectious Disease
Volume	84
Issue number	2
DOIs	https://doi.org/10.1016/j.diagmicrobio.2015.10.015
State	Published - 1 Feb 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

ESBL-producing Escherichia coli
Sequence type 131
Virulence factors

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10.1016/j.diagmicrobio.2015.10.015

Cite this

@article{711a10768cca485bb70752a4ec9c6cbb,

title = "Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia",

abstract = "We evaluated the molecular epidemiology and microbiological characteristics of extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) isolates that cause bacteremia in Korean hospitals, focusing especially on ST131. Our data suggest that ST131 isolates possessed more virulence traits and showed more multidrug resistance patterns than non-ST131 isolates. Among CTX-M-15 producers, the frequency of serum resistance was significantly higher in ST131 than in non-ST131. As in other parts of the world, the ESBL-EC ST131 clone has emerged and disseminated in both community and hospital settings in Korea, including in blood isolates in patients with bacteremia.",

keywords = "ESBL-producing Escherichia coli, Sequence type 131, Virulence factors",

author = "\{Korean Network for Study on Infectious Diseases (KONSID)\} and Cha, \{Min Kyeong\} and Kang, \{Cheol In\} and Kim, \{So Hyun\} and Cho, \{Sun Young\} and Ha, \{Young Eun\} and Wi, \{Yu Mi\} and Chung, \{Doo Ryeon\} and Peck, \{Kyong Ran\} and Song, \{Jae Hoon\} and Son, \{Jun Seong\} and Moon, \{Soo Youn\} and Kim, \{Choon Kwan\} and Lee, \{Seung Soon\} and Lee, \{Jeong A.\} and Kim, \{Yeon Sook\} and Sohn, \{Kyung Mok\} and Rhee, \{Ji Young\} and Jung, \{Sook In\} and Park, \{Kyung Hwa\} and Kang, \{Seung Ju\} and Kim, \{Shin Woo\} and Chang, \{Hyun Ha\} and Ryu, \{Seong Yeol\} and Kim, \{Hyun Ah\} and Kwon, \{Ki Tae\} and Lim, \{Min Hee\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = feb,

day = "1",

doi = "10.1016/j.diagmicrobio.2015.10.015",

language = "English",

volume = "84",

pages = "102--104",

journal = "Diagnostic Microbiology and Infectious Disease",

issn = "0732-8893",

publisher = "Elsevier Inc.",

number = "2",

}

Korean Network for Study on Infectious Diseases (KONSID) 2016, 'Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia', Diagnostic Microbiology and Infectious Disease, vol. 84, no. 2, pp. 102-104. https://doi.org/10.1016/j.diagmicrobio.2015.10.015

Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia. / Korean Network for Study on Infectious Diseases (KONSID).
In: Diagnostic Microbiology and Infectious Disease, Vol. 84, No. 2, 01.02.2016, p. 102-104.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia

AU - Korean Network for Study on Infectious Diseases (KONSID)

AU - Cha, Min Kyeong

AU - Kang, Cheol In

AU - Kim, So Hyun

AU - Cho, Sun Young

AU - Ha, Young Eun

AU - Wi, Yu Mi

AU - Chung, Doo Ryeon

AU - Peck, Kyong Ran

AU - Song, Jae Hoon

AU - Son, Jun Seong

AU - Moon, Soo Youn

AU - Kim, Choon Kwan

AU - Lee, Seung Soon

AU - Lee, Jeong A.

AU - Kim, Yeon Sook

AU - Sohn, Kyung Mok

AU - Rhee, Ji Young

AU - Jung, Sook In

AU - Park, Kyung Hwa

AU - Kang, Seung Ju

AU - Kim, Shin Woo

AU - Chang, Hyun Ha

AU - Ryu, Seong Yeol

AU - Kim, Hyun Ah

AU - Kwon, Ki Tae

AU - Lim, Min Hee

PY - 2016/2/1

Y1 - 2016/2/1

N2 - We evaluated the molecular epidemiology and microbiological characteristics of extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) isolates that cause bacteremia in Korean hospitals, focusing especially on ST131. Our data suggest that ST131 isolates possessed more virulence traits and showed more multidrug resistance patterns than non-ST131 isolates. Among CTX-M-15 producers, the frequency of serum resistance was significantly higher in ST131 than in non-ST131. As in other parts of the world, the ESBL-EC ST131 clone has emerged and disseminated in both community and hospital settings in Korea, including in blood isolates in patients with bacteremia.

AB - We evaluated the molecular epidemiology and microbiological characteristics of extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) isolates that cause bacteremia in Korean hospitals, focusing especially on ST131. Our data suggest that ST131 isolates possessed more virulence traits and showed more multidrug resistance patterns than non-ST131 isolates. Among CTX-M-15 producers, the frequency of serum resistance was significantly higher in ST131 than in non-ST131. As in other parts of the world, the ESBL-EC ST131 clone has emerged and disseminated in both community and hospital settings in Korea, including in blood isolates in patients with bacteremia.

KW - ESBL-producing Escherichia coli

KW - Sequence type 131

KW - Virulence factors

UR - https://www.scopus.com/pages/publications/84954370379

U2 - 10.1016/j.diagmicrobio.2015.10.015

DO - 10.1016/j.diagmicrobio.2015.10.015

M3 - Article

C2 - 26632660

AN - SCOPUS:84954370379

SN - 0732-8893

VL - 84

SP - 102

EP - 104

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 2

ER -

Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia

Abstract

UN SDGs

Keywords

Access to Document

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