Copper-catalyzed oxidative cyclization of α-hydroxyketones with o-phenylenediamines leading to quinoxalines

Chan Sik Cho; Sung Gi Oh

doi:10.1016/j.molcata.2007.07.014

Copper-catalyzed oxidative cyclization of α-hydroxyketones with o-phenylenediamines leading to quinoxalines

Chan Sik Cho
, Sung Gi Oh

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

Abstract

α-Hydroxyketones are oxidatively cyclized with o-phenylenediamines in toluene at 120 °C under an atmosphere of air in the presence of a catalytic amount of a copper catalyst along with powdered 4A molecular sieves to afford the corresponding quinoxalines in high yields. The reaction is applicable to a wide range of α-hydroxyketones which have various aryl and alkyl groups attached to carbonyl carbon.

Original language	English
Pages (from-to)	205-210
Number of pages	6
Journal	Journal of Molecular Catalysis A: Chemical
Volume	276
Issue number	1-2
DOIs	https://doi.org/10.1016/j.molcata.2007.07.014
State	Published - 17 Oct 2007

Keywords

α-Hydroxyketones
Copper catalyst
o-Phenylenediamines
Oxidative cyclization
Quinoxalines

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10.1016/j.molcata.2007.07.014

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title = "Copper-catalyzed oxidative cyclization of α-hydroxyketones with o-phenylenediamines leading to quinoxalines",

abstract = "α-Hydroxyketones are oxidatively cyclized with o-phenylenediamines in toluene at 120 °C under an atmosphere of air in the presence of a catalytic amount of a copper catalyst along with powdered 4A molecular sieves to afford the corresponding quinoxalines in high yields. The reaction is applicable to a wide range of α-hydroxyketones which have various aryl and alkyl groups attached to carbonyl carbon.",

keywords = "α-Hydroxyketones, Copper catalyst, o-Phenylenediamines, Oxidative cyclization, Quinoxalines",

author = "Cho, \{Chan Sik\} and Oh, \{Sung Gi\}",

year = "2007",

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doi = "10.1016/j.molcata.2007.07.014",

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AU - Cho, Chan Sik

AU - Oh, Sung Gi

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Y1 - 2007/10/17

N2 - α-Hydroxyketones are oxidatively cyclized with o-phenylenediamines in toluene at 120 °C under an atmosphere of air in the presence of a catalytic amount of a copper catalyst along with powdered 4A molecular sieves to afford the corresponding quinoxalines in high yields. The reaction is applicable to a wide range of α-hydroxyketones which have various aryl and alkyl groups attached to carbonyl carbon.

AB - α-Hydroxyketones are oxidatively cyclized with o-phenylenediamines in toluene at 120 °C under an atmosphere of air in the presence of a catalytic amount of a copper catalyst along with powdered 4A molecular sieves to afford the corresponding quinoxalines in high yields. The reaction is applicable to a wide range of α-hydroxyketones which have various aryl and alkyl groups attached to carbonyl carbon.

KW - α-Hydroxyketones

KW - Copper catalyst

KW - o-Phenylenediamines

KW - Oxidative cyclization

KW - Quinoxalines

UR - https://www.scopus.com/pages/publications/34548536999

U2 - 10.1016/j.molcata.2007.07.014

DO - 10.1016/j.molcata.2007.07.014

M3 - Article

AN - SCOPUS:34548536999

SN - 1381-1169

VL - 276

SP - 205

EP - 210

JO - Journal of Molecular Catalysis A: Chemical

JF - Journal of Molecular Catalysis A: Chemical

IS - 1-2

ER -

Copper-catalyzed oxidative cyclization of α-hydroxyketones with o-phenylenediamines leading to quinoxalines

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Keywords

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