Copper powder-catalyzed C-N bond formation of arylhydrazones of 2-bromobenzaldehydes leading to 1-aryl-1 H-indazoles

Hye Kyung Lee, Chan Sik Cho

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Arylhydrazones of 2-bromobenzaldehydes and its analogs are cyclized in PEG-400 at 110C in the presence of a catalytic amount of copper powder along with NaOtBu to give 1-aryl-1H-indazole derivatives in good yields.

Original languageEnglish
Pages (from-to)915-921
Number of pages7
JournalSynthetic Communications
Volume43
Issue number6
DOIs
StatePublished - 2 Jan 2013

Keywords

  • 1-Aryl-1 H-indazoles
  • arylhydrazones
  • C-N bond formation
  • copper powder

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