Copper(I) salt/PEG-400 catalysis in one-pot direct synthesis of 1-aryl-1H-indazoles from 2-bromobenzaldehydes and arylhydrazines

Yeon Kyu Bae, Chan Sik Cho

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

2-Bromobenzaldehydes are condensed and cyclized with arylhydrazines (or their hydrochlorides) in PEG-400 at 110 °C in the presence of a catalytic amount of a copper(I) salt along with a base to give 1-aryl-1H-indazoles in high yields.

Original languageEnglish
Pages (from-to)224-227
Number of pages4
JournalApplied Organometallic Chemistry
Volume27
Issue number4
DOIs
StatePublished - Apr 2013

Keywords

  • 1-aryl-1H-indazoles
  • arylhydrazines
  • Câ€N bond formation
  • copper(I) salts
  • cyclization
  • PEG-400

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