CuI/amino acid catalysis in coupling and cyclization of β-bromo-α,β-unsaturated carboxylic acids with terminal alkynes leading to alkylidenefuranones

Son Long Ho; Chan Sik Cho; Heung Jin Choi; Ho Sang Sohn

doi:10.1002/aoc.2963

CuI/amino acid catalysis in coupling and cyclization of β-bromo-α,β-unsaturated carboxylic acids with terminal alkynes leading to alkylidenefuranones

Son Long Ho, Chan Sik Cho, Heung Jin Choi, Ho Sang Sohn

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

β-Bromo-α,β-unsaturated carboxylic acids are coupled and cyclized with terminal alkynes in DMF at 110°C in the presence of a catalytic amount of CuI and amino acid along with a base to give alkylidenefuranones in good yields. Similar reaction under microwave irradiation also gave alkylidenefuranones in higher yields.

Original language	English
Pages (from-to)	277-282
Number of pages	6
Journal	Applied Organometallic Chemistry
Volume	27
Issue number	5
DOIs	https://doi.org/10.1002/aoc.2963
State	Published - May 2013

Keywords

alkylidenefuranones
amino acids
cyclization
terminal alkynes
β-bromo-α,β-unsaturated carboxylic acids

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10.1002/aoc.2963

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title = "CuI/amino acid catalysis in coupling and cyclization of β-bromo-α,β-unsaturated carboxylic acids with terminal alkynes leading to alkylidenefuranones",

abstract = "β-Bromo-α,β-unsaturated carboxylic acids are coupled and cyclized with terminal alkynes in DMF at 110°C in the presence of a catalytic amount of CuI and amino acid along with a base to give alkylidenefuranones in good yields. Similar reaction under microwave irradiation also gave alkylidenefuranones in higher yields.",

keywords = "alkylidenefuranones, amino acids, cyclization, terminal alkynes, β-bromo-α,β-unsaturated carboxylic acids",

author = "Ho, \{Son Long\} and Cho, \{Chan Sik\} and Choi, \{Heung Jin\} and Sohn, \{Ho Sang\}",

year = "2013",

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doi = "10.1002/aoc.2963",

language = "English",

volume = "27",

pages = "277--282",

journal = "Applied Organometallic Chemistry",

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T1 - CuI/amino acid catalysis in coupling and cyclization of β-bromo-α,β-unsaturated carboxylic acids with terminal alkynes leading to alkylidenefuranones

AU - Ho, Son Long

AU - Cho, Chan Sik

AU - Choi, Heung Jin

AU - Sohn, Ho Sang

PY - 2013/5

Y1 - 2013/5

N2 - β-Bromo-α,β-unsaturated carboxylic acids are coupled and cyclized with terminal alkynes in DMF at 110°C in the presence of a catalytic amount of CuI and amino acid along with a base to give alkylidenefuranones in good yields. Similar reaction under microwave irradiation also gave alkylidenefuranones in higher yields.

AB - β-Bromo-α,β-unsaturated carboxylic acids are coupled and cyclized with terminal alkynes in DMF at 110°C in the presence of a catalytic amount of CuI and amino acid along with a base to give alkylidenefuranones in good yields. Similar reaction under microwave irradiation also gave alkylidenefuranones in higher yields.

KW - alkylidenefuranones

KW - amino acids

KW - cyclization

KW - terminal alkynes

KW - β-bromo-α,β-unsaturated carboxylic acids

UR - https://www.scopus.com/pages/publications/84876577943

U2 - 10.1002/aoc.2963

DO - 10.1002/aoc.2963

M3 - Article

AN - SCOPUS:84876577943

SN - 0268-2605

VL - 27

SP - 277

EP - 282

JO - Applied Organometallic Chemistry

JF - Applied Organometallic Chemistry

IS - 5

ER -

CuI/amino acid catalysis in coupling and cyclization of β-bromo-α,β-unsaturated carboxylic acids with terminal alkynes leading to alkylidenefuranones

Abstract

Keywords

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