Abstract
Artemisia capillaris THUNB is a perennial herb that belongs to the family Compositae spp and the most common plant among the various herbal folk remedies used in treatment of abdominal pain, hepatitis, chronic liver disease, jaundice and coughing in Korea. This experiment was conducted to investigate cytotoxic effects of Artemisia capillaris extracts on the Hepa-1c1c7 and Sarcoma 180 cancer cells on in vitro experimental tests. On in vitro tests using MTT assay and SRB assay, the extracts showed prominent cytotoxic effects on the two kinds of cancer cell lines, respectively. Antitumor effects appeared in the concentration of over 250 μg/mL of both ethanol and ethyl acetate extract, over 500 μg/mL of methanol extract, over 5000 μg/mL in water extract and over 50% cytotoxicity on the Hepa-1c1c7 and Sarcoma 180. The results suggest that Artemisia capillaris extracts have prominent cytotoxic effects on the cancer cell lines Hepa-1c1c7 and Sarcoma 180.
| Original language | English |
|---|---|
| Pages (from-to) | 367-371 |
| Number of pages | 5 |
| Journal | Journal of Veterinary Clinics |
| Volume | 24 |
| Issue number | 3 |
| State | Published - Sep 2007 |
Keywords
- Artemisia capillaris
- Cytotoxic effect
- Extract
- Hepa-1c1c7
- MTT assay
- Sarcoma 180
- SRB assay
